1 Smooth muscleeffects: Citrus grandis‘Tomentosa’could shift the concentration-response curves of histamine. Acetylcholine andKCl, BaCl₂, CaCl₂ to the rightward and the maximaleffects were decreased. In addition, BaCl₂> KCl > CaCl₂ >His >Ach could affect thecontraction of calcium transporting into cell [1].

2 Dissolving sputum andAnti-inflammation: Citrus grandis ‘Tomentosa’possess the role of dissolving sputum and anti-inflammation, the role intensityof MJH was bigger than that of GJH. The quality of MJH is better than GJH atthe angle of pharmacodynamics. It is coincident with the traditional opinionthat the genuine material is good [2,3].

chemical composition：

Pharmacological Actions:

[1] Jun Guan, Zhao-hua Wu, Wan-zheng Wu, Citrus grandis ‘Tomentosa’ extract on isolated guinea pig tracheal smooth muscle, Journal of Chinese Medicinal Materials, 2004, 27(7): 515.

[2] Comparison on Dissolving Sputum and Anti-inflammation of “Mao Ju Hong” and “Guang Ju Hong”, Journal of Chinese Medicinal Materials, 2004,27(2):122.

[3] Hai-dan Lin, Wei-wei Su, Research Advance on Citrus grandis ‘Tomentosa’, Journal of Chinese Medicinal Materials, 2001, 24(8): 608.

[4]albaebr,et al.phytochemistry,1969,(8):127.

[5]quisumbinge.medicinalplants of the philippines,1978:452.

[6]mizunom,etal.chem pharm bull,1991,39(4):945.

[7] chinese academy of medical sciences institute of health. food composition table.first edition.beijng: people's health publishing house, 1977:170.

[8] huang meisheng,shen yugang.r-hplc determination of the orange-red in naringin[j]. chinese traditional and herbal drugs,1990,21(5):15.

[9] chen lianjian,li ting,li cheng.citrus grandis by supercritical co2 extract gc-ms analysis[j]. journal of chinese medicinal materials,2003,26(8):559-560.

[10] zhang li-jian,cai chun,wang xiu-ji. comparison of volatile oil components in tomentose pummelo fruit,red tangerine peel and pummelo peel [j]. journal of guangdong medical college,2006,24(4):344-345.

[11] li chun1,2, xiang neng-jun1, shen hong-lin1,3,etal. studies on chemical constituents of exocarpium citri grandis volatile oil[j]. fine chemical intermediates,2009,39(4):65-67.

[12]yuan xujiang,lin li,chen zhixia.the research of phenolic compounds in pummelo peel .chinese traditional and herbal drugs,2004,35(5):498-500.

pharmacological action：

[1] guang junliang,wu zhaohua,wu wanzheng.exocarpium cirei grandis’s extraction on isolated guinea pig tracheal smooth muscle [j].journal of chinese medicinal materials,2004,27(7):515.

[2] zhang xiuming1,chen zhixia2, lin li3. comparison on dissolving sputum and anti-inflammation of "mao ju hong" and "guang ju hong[j]. journal of chinese medicinal materials,2004,27(2):122.

[3]lin haidan,su weiwei.the progress of the study on exocarpium cirei grandis[j]. journal of chinese medicinal materials,2001,24(8):608.

clinical research：

[1].chen yongnian.60 cases of the treatment of pertussis by oral end of the gall bladder, dried tangerine peel, the injection of vitamin c, glue the small calcium[j].chinese journal of integrated traditional and western medicine,1985,5(11):695.

[2] jiang yiming,etal. a sequential analysis of emergency treatment of paroxysmal supraventricular tachycardia with injection of qingpi

[j]. chinese journal of integrated traditional and western medicine,1984,4(3):162.

[3]chen ruxing,etal.the clinical observation of anti-shock action on the injection of qingpi .shanghai journal of traditional chinese medicine,1987,(2):2.

[4] fu huaqun chen anqiu li jianye. clinical study of the emulsion of orange peel oil and cdta to dissolve retained bile duct stones[j]. chinese journal of integrated traditional and western medicine,1985,5(10):595-598,578.

[5] ta shurong.the treatment of 67 cases acute viral hepatitis by qinghuang powder .sichuan journal of traditional chinese medicine.1994,12(3):21.

[6]yang fengqin. fresh orange peel steep water on behalf of the tea in the treatment of chronic bronchitis. heilongjiang journal of traditonal chinese medicine.1990,(6):37.

[7]zhang shouhai.the treatment of burns by cellulite solution.chinese journal for clinicians.1975,(4):11.

[8] su wenshao,liu xiaogang,liu junhua.the treatments of 164 cases of human scabies mite by orange peel’s extraction .jilin journal of traditional chinese medicine.1991,(3):27.

[9]ding linzhang,huang shunxian.1 case of gastrointestinal perforation caused by the oral orange peel’s solution.chinese journal of integrated traditional and western medicine,1992,12(3):156.

toxicology：

[1]ke mingqing.the physicochemical and pharmacological properties of active ingredients on chinese herbal medicine,second edition.changsha: hunan science and technology press, 1982:91.