| [English Name] | Grosvener Siraitia | |
| [Chinese Name] | 罗汉果 | |
| [Pinying Name] | Luohanguo | |
| [Latin Name] | Fructus Siraitiae Grosvenorii | |
| [Genera] | Cucurbitaceae | |
| [Efficacy] | zhikepingchuanyao | |
| [Pictures] | Plant picture | Drug picture |
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| [Characteristics] | ||
| [Ecology] | Grosvener Siraitia prefers cool shade and the environment with high day-night temperature difference and long frost-free period.It doesn’t resistant to high temperature, rattans grow rapidity in the temperature between 22 to |
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| [Chemical composition] | ||
| [Pharmacological activities] |
1. The water extract of Siraitia Grosvenori has obvious effect on eliminating phlem[1]. 2. Mogrosides has certain up-regulation on cellular immunity in the GTX-induced immunosuppressive mice[2]. 3. Mogroside extracts have obvious glucose-lowering effect on hyperglycemic mice，its mechanism may be related with improving antioxidation level and restoring the blood lipid levels of hyperglycemic mice[3,4]． 4. Extracts from fruits of Siraitia grosvenori have antioxidant effects while Mogrosides were the main antioxidant components of the extract[8,9]. 5. Flavone from M.grosvenori have functions of antithrombogenicity, inhibition of thrombus formation, aggregation of platelet and could decrease the level of TG,TC and HDL[10]. 6. The water extract of Siraitia grosvenori also exhibits other effects such as protecting liver, anti-tumor, antibacterial and so on[5-7]. |
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| [Clinical trial] | Chronic pharyngitis: 121 cases were treated with Luohanguo (Grosvener Siraitia)Yanhou tablet. 4 times a day, 2 week as 1 course. Results showed that 61 cases were cured (50.4%), 47 cases were markedly effective (38.8%), the total efficiency was 97.5% [1]. |
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| [Traditional usage] |
1.Loss of voice due to sore throat 2.Cough with profuse phlegm, dry mouth and throat 3. Acute and chronic bronchitis, tonsillitis, sore throat, constipation |
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| [References] |
Pharmacological actions: [2] Wang Qin, Wang Kun, Dai Shengming, et al. Regulation on the Immunological Effect of Mogrosides in the Mice. Chinese Herbal Medicine, 2001,24(11):811. [4] ZHANG Li-qin, QI Xiang-yang, CHEN Wei-jun, et al. Efect of Mogroside extracts on blood glucose，blood lipid and antioxidation of hyperglycemic mice induced by Alloxan. Chinese Pharmacological Bulletin, 2006,22(2):237. [5] Wang Qin, Li Ai-yuan, Li Xian-ping,et al. Study on the pharmacological actions of Siraitia Grosvenori Chin J Chin Mat Med, 1999,24(7):425. [6] Mu Dao-xiao-fu. Effects on the anti-tumor of mogroside V in Siraitia Grosvenori. Foreign medical-volume of traditional Chinese medicine, 2003,25(3):174. [7] LI Hai-Bin, WANG Yong, BAI Xian-fang, et al. Influence of Microwave Irradiation on the Active Components of Luohanguo Extracts. FINE CHEMICALS, 2006,23(3):264. [8] ZHANG Li-qin, QI Xiang-yang, CHEN Wei-jun, et al. Study on in vitro Antioxidant Activity of Extracts from Siraitia grosvenori Fruits. Food Science, 2006,27(1):213. [9] Hao Gui- xia. The Scavenging Effect of Siraitia Grosvenorii Extracts on Free Radical. [10] Chen Quanbin, Shen Zhongsu, Wei Zhengbo, et al. Study on the Pharmacological Function of Stimulate Circulation to End Stasis of Flavone from Momordica grosvenori. Guangxi Sciences, 2005,12(4):316～319. |
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