[English Name] | Sweet Broomwort Herb | |
[Chinese Name] | 冰糖草 | |
[Pinying Name] | Bingtangcao | |
[Latin Name] | Herba Scopariae | |
[Genera] | Scrophulariaceae | |
[Efficacy] | Antipyretic drug | |
[Pictures] | Plant picture | Drug picture |
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[Plant morphology] | ||
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[Characteristics] | ||
[Ecology] | It grows in field side、village side、wetland beside road. | |
[Chemical composition] | The whole plant contains friedelin, glutinol, α-amyrin, betulinic acid, ifflaionic acid, dulcioic acid, scoparic acid A, scoparic acid B, scoparic acid C, scopadulcic acid A, scopadulcic acid B, scopadulin, scoparinol, dulcinol, benzoxazolinone, 6-methoxybenzoxazolinone, 5,7-dihydroxy-3′,4′,6,8-tetramethoxyflavone, 5,7,8,3′,4′,5′-hexahydroxyflavone-7-O-β-D-glucuronide, apigenin, scutellarein, luteolin, vicenin-2, linarin, vitexin, isovitexin, scutellarin, scutellarin methyl ester, luteolin-7-glucosid, acacetin, p-coumaric acid, dulciol, amellin[1]; The aerial part contains dulciol, scopadiol; The leave contains glutinol, 6-methoxybenzoxazzolinone, acacetin, scopadulcic acid A[1]; The roots contains β-sitosterol, hexacosanol, D-mannitol, 6-methoxybenzoxazzolinone, coixol[1]. |
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[Pharmacological activities] |
1 Antiviral activity: The dulcioicacid B contained in Sweet Broomwort Herb can inhibit the proliferation of the virus in vitro, which function by interfering with the early growth of virus. This product can affect the early course of infection of herpes simplex virus. Oral or intraperitoneal injection of 100 ~ 200mg/kg can delay the appearance of virus-inoculated animal herpes lesions and prolong the survival time [1]. 2 Inhibition of the gastric proton pump: This product can significantly inhibit the gastric proton pump (H+-K+-ATP enzyme), this inhibition is reversible and competitive with the half-inhibitory concentration (IC50) of 20~30μmol/L, and this product also has a protective effect on stomach [2] [3]. 3 Anticancer activity: 5,7-dihydroxy-3,,4,,6,8-tetramethoxyflavone contained in Sweet Broomwort Herb has cytotoxic effect on Hela229 cell lines、HelaS3 cell lines、HEp-2 cell lines and six kinds of normal human tissue cell lines, and the sensitivity of function is higher for the former [4]. 4 Hypoglycemic activity: Oral injection of 15 ~ 20mg/kg of Amellin, an important component contained in Sweet Broomwort Herb, can alleviate the symptoms of diabetic patients, both the urine and blood glucose have limited decline in within 30 days [5]. |
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[Traditional usage] |
1. Eczema, reddish sudamen 2. Dropsical beriberi 3. Erysipelas 4. Measles 5. Dysphoria caused by liver fire in children 6. Exogenous fever in children, enteritis and dysuria |
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[References] |
Chemical composition: [1]Nanjing University of Chinese Medicine. Chinese Dictionary (Volume two). Second Edition. Shanghai: Shanghai Science and Technology Press, 2006:2954. Pharmacological effects: [1]Hayashi Kl.Antiwitral Res,1988,9(6):345. [2]Asano S.J Biol Chen,1990,265(36):22167. [3]Hayashi T.Chem Pharm Bull,1990,38(10):2740. [4]Hayashi T.Chem Pharm Bull,1988,36(2):4849. [5] The new Jiangsu School of Medicine. Chinese Dictionary (Volume two). First Edition. Shanghai Science and Technology Press, 1977:2132. |