[English Name] | White Tremella | |
[Chinese Name] | 银耳 | |
[Pinying Name] | Yiner | |
[Latin Name] | Fuciformis Tremella | |
[Genera] | Tremellaceae | |
[Efficacy] | buyao | |
[Pictures] | Plant picture | Drug picture |
|
|
|
[Alias] | ||
[Source] | ||
[Plant morphology] | ||
[Distribution] | ||
[Gathering and processing] | ||
[Characteristics] | ||
[Ecology] | It is grows in broad-leaved tree’s corruption wood in summer. | |
[Chemical composition] | It contains polysaccharide TP-1, glycoprotein TP, cell wall polysaccha, glucuronoxylomannan, TP, TSP, TF-B and TF-C, neutral polysacc, acidic heteroglycans AC,BC, TF-A, TF-B, TF-C. Lipid composition(The sterols): ergosterol, ergosta-5,7-dien-3β-ol, ergosta-7-en-3β-ol; (fatty acid):undecanoic acid, n-dedecanoic acid, tridecanoic acid, n-tetradecanoic acid, pentadecanoic acid, n-hexadecanoic acid, n-octadecanoic acid, hexadec-9-enoic acid, octadec-9-enoic acid, octadeca-9,12-dienoic acid; (phospholipid):phosphatidyl ethanolamine, phosphatidyl glycerol, phosphatidyl serine, phasphatidyl choline, phosphatidyl inositol. Besides, the mycelium contains sanitanin A、B、C、D[1]. | |
[Pharmacological activities] |
1.Effect on immune function of: (1) humoralimmune function : polysaccharide conjugates of White Tremella and lentinan has significantlyimproved HC50[1] of tumor-bearing mice S-180. (2) effect oncell immune function : in vitro, polysaccharides from White Tremella can induce human lymphocyte transformation, itsactivity is similar to plant lectins; in vivo ,it can improve the conversionrate of leukemia in human lymphocytes [2]. It can significantly enhance the splenic lymphocyte proliferation inmice, while it is obviously antagonistic cells of immunosuppression induced by6-Mercaptopurine [3]. In vitro , polysaccharide conjugates of White Tremella achieved immunecells regulation function [4]. (3) Effect on nonspecific immune function polysaccharide conjugates of White Tremella and lentinan canincrease nonspecific immune function of tumor-bearing mice [5]. (4) Effect on immunological organ weights polysaccharides from White Tremella can significantly increase the weights of spleen in mice,by subcutaneous injection (100mg/kg)[6]. 2.Effect on anti-tumor: polysaccharidesfrom White Tremella and IL-2 has synergistic effects on activating spleen cellsand antitumor, but no discernible impact on the main organ in the body [7].It also plays a protective role in the hematopoietic function of radiation andchemical damage in mice [8]. 3. Anti-aging: polysaccharides from White Tremellaenhanced immune function and played anti-aging effects [9]. At thesame time, it can significantly be against d-Galactose-induced mice onConA-induced inhibition of lymphocyte transformation, increase the contents of IL-2and IL-6 in aging mice, which indicates that polysaccharides from Tremella canenhance immune function in aging mice, promote the proliferation of cells,prevents aging [10]. 4.lowering blood sugar and lipid: threedoses of 250, 500 and 1000mg/kg of polysaccharides from White Tremella cansignificantly reduce levels of blood glucose in diabetic mice induced byalloxan, reduce hyperglycemia animal and normal animal blood sugar levels,increase serum insulin level [11]. Polysaccharides from WhiteTremella may prevent the formation of hypercholesterolemia mice [12]. 5.blood anticoagulant and antithrombotic: Polysaccharidesfrom White Tremella in vitro and in vivo applications. Different routes of administrationhave a significantly strong anticoagulant activity,it works best particularlyin the oral [13]. The doses 27.8mg/kg and 41.7mg/kg of polysaccharidesfrom White Tremella by intraperitoneal injection in rabbit, can significantlyextend specific thrombosis and fibrin thrombi formation time, reduce the lengthof thrombus, the number of platelets and blood viscosity and platelet adhesionrate; decrease the plasma fibrinogen, high fibrinolytic enzyme,which shows thatit has distinct antithrombotic effect [14]. 6.anti-radiation: The three doses 6mg/kg,12mg/kg, 24mg/kg of polysaccharides from White Tremella has a protective rolein hematopoietic system induced by 137Csγ-ray irradiation in mice [8]. |
|
[Clinical trial] | 1. Chronic active hepatitis: Yinerbaozi intestines dissolvingcapsule five capsules, three times per day. 3 months as a course of treatment, totreat for 2 courses .The results showed the Yinerbaozi capsule can improvesymptoms, signs, fall enzyme which had curative effect, and can promote eantigen negativity humoral immune suppression, improve immune cells. No badreaction[1]. 2. Chemotherapy induced leukopenia: During chemotherapy to eatYiner daily steamed pork, ,8 ~ 10 days as one courses of treatment. During treatment need not Other white bloodcell increase drug, The results show that has the obvious increase white bloodcells . |
|
[Properties] | Taste: sweet, bland; property: neutral; belong to lung, stomach, kidney chnnels. |
|
[Medical and other Uses] | Function: nourish deficiency and promote the production of body fluid, moisten the lung and nourish stomach Syndromes to be treated: Consumptive cough, blood-stained sputum, thirst, weak after the illness, shortness of breath, fatigue |
|
[Dosage] | Oral administration: decoction, 3 |
|
[Cautions] | Forbid to be used in the patients with cough due to wind-cold evil and moist heat |
|
[Traditional usage] |
1. Moistening the lung,relieving cough and nourishing the body 2. Yin deficiency of the lung, cough, scanty phlegm and thirst 3. Heat syndrome impairing the fluid, inclination to drinking due to thirst 4. Radiotherapy and chemotherapy periods of cancer 5. Primary hypertension |
|
[Toxicological studies] | ||
[Pharmaceutical preparations] | ||
[References] |
Chemical Composition: [1] State Administration Of Traditional Chinese Materia Medica Editorial Board."" Chinese Materia Medica. Shanghai: Shanghai Science And Technology Press,1999,3:514( Total5340). Pharmacological Effect: [1] Xu Qingle, Yang Feng, Mushroom Polysaccharide Of Tremella Polysaccharides On S180 Tumor-Bearing Mice Immune Function Of Zhejiang Clinical Medicine,2002,4(10):730 [2] Chen Ziqi, Wang Zhancun Tremella Polysaccharide On Hematopoietic And Immune Effect Of Clinical Observation. Chinese Journal Of Radiological Medicine And Protection,198,4(3):54 [3]Xia Dong, Lin Zb. Effets Of Tremella Polysaccharides On Immune Function In Mice. Acta Ph Sinica,1989,10(5): 453. [4] Hu Tingjun, Liang Jilan, Cheng Fusheng, Etc. Effect Of Tremella Polysaccharides On Protein Kinase C Activity In Murine Spleen Lymphocytes . Chinese Herbal Medicine,2005,36(1):81 [5] Jiang Tienan, Zhang Yuguang, Li Zhiwang, Et Al. Tremella On Mouse Peritoneal Macrophages Function And Ultrastructure. Journal Of Electronics,1990,9(3):104 [6] Lin Zhibin, Qin Zelian, Xia Honglin, Et Al. Tremella Polysaccharides On Immune Function Of Mice Liver Homogenate And Cytochrome P-450content Were Investigated. Chinese Pharmacological Sinica,1985,6(3):201 [7] Dong Zhiheng, Song Adorable, Covered In . On The Experiment Of Hepatocarcinoma With Homogenous Spleenocytes Activated By Il-2 And Tremella Polysaccharide . Journal Of Beihua University: Natural Science Edition,2004,5(1):22 [8] Xu Wenqing, Gao Wen Yuan, Shen Xiu, Etc. Protective Effect Study Of Polysaccharides From Tremella Fuciformis On Hematopoietic Function In Radiation-Injured Mice . International Journal Of Radiation Medicine And Nuclear Medicine,2006,30(2):114 [9] Nie Wei, Zhang Yongxiang, Zhou Jinhuang. The Tremella Polysaccharides Pharmacological Study Of Pharmacology And Clinic Of Chinese Traditional Medicine,2000,16(4):44 [10] Li Yan, Liu Xiaoli, Pei Suping, Et Al. Effect Of Tremella Polysaccharides On The Immune Function Of Experimental Aging Model Mice . The Influence Of Chinese Journal Of Clinical Nutrition,2005,13(4):228 [11] Jiang Xiulian, Hong Chonghua Iron, Gold, Etc. Of Tremella Polysaccharide On Four In Alloxan Diabetic Mice Hypoglycemic Effect. Changbai Mountain Traditional Chinese Medicine Research And Development,1995,4(2):48 [12] To Build And, Chen Qionghua. The Agaric Polysaccharide, Tremella Polysaccharide And Tremella Polysaccharide With Function Of Reducing Blood Lipid. Journal Of China Medicine University,1989,20(6):344 [13] To Build And, Chen Qionghua Black Fungus Polysaccharide Of Tremella Polysaccharide, Full, Tremella Polysaccharide Anticoagulant Effect. Journal Of China Medicine University,1987,18(2):137 [14] To Build And, Chen Qionghua. The Agaric Polysaccharide Of Tremella Polysaccharide Of Tremella Fuciformis Berk, And Full Polysaccharide On Experimental Thrombus Formation In Rats. Journal Of China Medicine University,1990,21(1):39 Clinical Trials: [1] Li Qiangzhong Tremella Polysaccharide Enteric-Coated Capsules In Treatment Of Chronic Active Hepatitis Clinical Research On Infectious Disease Information,2006,19(4):201 [2] Tang Huifang Tremella Steamed Meat Treatment Of Leukopenia Caused By Chemotherapy Curative Effect Observation. Chinese Journal Of Clinical Medicine Research,2005137:14842. Toxicology: [1] Shire Ning, Chen Qionghua. The Polysaccharide Of Tremella Fuciformis Berkeley Isolation, Analysis And Biological Activities Of Fungi Sinica,1988,7(3):166 [2] Jia Hanqing, Ann Zheng Shuqin Yingling, Tremella Polysaccharide J Chronic Toxicity Test. Jia Musi Medical Journal,1990,13(2):97 |