1 Anti-cancer: The IC₅₀ of anti-cancer activecomponents of Fig Residues on U937, 95D and AGS cells were 70.125 μg·mL^-1,127.957 μg·mL^-1,116.000 μg·mL^-1; The anti-cancer activecomponents of Fig Residues inhibited 49.3% of the transplanted liver cancer inthe mice. The anti-tumor effect of FCPS might relevent to increasing theactivity of SOD GSH-PX and decreasing the levels of MDA in S 180 -bearing mice[1]. FE has cytotoxicity on some human lung cancer cells, but little effect onnormal cells at the certain concentration, and its mechanism of activity mightbe associated with the inhibition of apoptosis of cancer cells [2]. FFL hascytotoxicity on some human cancer cells, but little effect on normal cells atcertain concentration, and its mechanism of activity might be associated withthe inhibition of DNA synthesis of cancer cells, induction apoptosis and cellcycle arrest of cancer cells [3,4].

2 Immunologic function: Fig Residues could enhanceimmunologic function of tumor-loading mice. Polysaccharide of Ficus caricapossesses action of immunologic enhancement [5]. FCPS can significantly enhanceresponse of DTH in cyclophosphamide intoxicated mice and mice under stress.FCPS could enhance immunofunction of immunodeficient mice [6]. FCPS possesses immunologicenhancement [7].

3 Anti-fatigue and Hypoxia tolerance: low dosagegroup (0.22g/kg), median dosage group (0.67g/kg)and high dosage group (2g/kg)ofthe water extract of Ficus carica, perfusing them into the stomach for 5 weeks,observe the swimming time of the control group and the different dosage groupsto make sure the anti-fatigue effect of the water extract of Ficus carica [8]The water extract of ficus has the effect of anti-fatigue,its changes may beinfluenced through increasing tNOS and cNOS in serum. fig water extract ofdifferent concentrations (0.22, 2.166, 7 and 200 mg/ml respectively for thefour groups) was given into the rats’ stomach for a continuous 30 days Figwater extract is proved to have anti-fatigue and hypoxia tolerance function onrats [9].

4 Antimutagenic effects: The water extract of ficus carica could decrease thefrequncy of micronuclei induced by CP in mice peripheral lymphocytes within thedosage 50-200mg/ml (P<0.05) [10].

5 Analgesic activity: Ficus carica have been found to haveanalgesic activity [11].

6 Antioxidant activity: Ficus carica have stronger antioxidant capability [12].

7 Laxative effects: Ficuscarica made as the food aperients [11].

8 The others: Hypotension ficus carica possessed a considerablehypotensive action [13].

9 Toxicity: Rats injected milk of immaturatefruit (0.02 m1), or home rabbit (0.05 m1), can make the animal immediate death.The anatomy is visible for damage internal capillary; Intraperitoneal injectionalso get similar results; Subcutaneous injection can cause local tissuenecrosis; Oral is non-toxic [14, 15].

Wuhuaguo (fig)

1. Condyloma acuminate: take the fresh wuhuaguo (fig) milk liquidinunction on the warts and basement department (avoid normal skin as far aspossible) and take a hip bath with radix sophorae flavescentis soup. 5 minuteslater could see the verrucous body congestion edema, with minor aches anditching, application after herbal fumigation, the symptom is reduced, no scarleft. Results: 21 cases of acuteness wet wart, 4days cured 5 cases, 5 days cured7 cases, 6 days cured 8 cases and 7days cured 1 case ^[1]

2. Hemorrhoids: 7 grains of wuhuaguo (fig) add right amount ofhoney, steaming with slow fire and then take it. 7 days a course. Results:Among the 30 patients 20 were cured, 8 were markedly improved, 2 cases invalid,the total effective rate was 93.3% ^[2].

3. Children diarrhea: zuoshupi(oak bark)50g, wuhuaguo 7 grains, soak in boiling water and fume the soles with the steam,soaked the feet in the medicine juice and elution the knee-joint and the belowpart until the temperature fall to 30℃ or so, twice a day and 7days for aperiod of treatment. Treat 136 pediatric patients with diarrhea. Results: 105patients were cured after 4 days treatment, 26 were obviously improved after 6days treatment, 5 cases invalid. ^[3] <!--[if !vml]--><!--[endif]-->

4. Chronic superficial gastritis: The treatment group use weichangshudecoction (dangsen (codonopsis pilosula), ganjiang (rhizome zingiberis), chaobaishao(fried radix paeoniae alba), wuhuaguo (fig) etc.), 1 agent every day, 15 daysfor a course of treatment. The control group use SanJiu WeiTai electuary, twicea day. Both groups take 2-5 courses. Results: The effective rate of treatmentgroup was obviously superior to the control group ^[4]

1. Swolling and pain due to ulcer and sores

2. Beriberis or tinea pedis

3. Bones and muscles pain

4. Esophageal cancer

5. Gastric cancer, intestinal cancer

6. Bladder cancer

7. Pharyngodynia

8. Hoarseness due to lung-heat

9. Dry and chronic cough

10. Hypogalactia

11. Diarrhea due to dyspepsia

12. Chronic dysentery

13. Constipation

14. Chronic diarrhea

15. Bleeding hemorrhoids

16. Impotence

[1] Zhen-bin Wang, Hai-le Ma, Study on anti-cancer components of Fig Residues with suppercritical fluid CO₂ extracting technique, China Journal of Chinese Materia Medica, 2005, 30 (18): 1443．

[2] Wei-juan Dai, Wei-fa Zhong, Duan-yun Si et al., Effect of FCPS on blood serum MDA, SOD and GSH-PX of S180-Bearing Mice, Journal of Jining Medical College, 2002,25(1):20．

[3] Liu Jun, Bai-jiang Zhang, Proliferation inhibition and apoptosis induction of fig extract on human lung cancer cells, Chin Cancer Prev Treat., 2008, 15 (9): 665．

[4] Jing Wang, Xiu-jie Wang, Ping Lin, Proliferation Inhibition and Apoptosis Induction of Fig Fruit Latex on Human Cancer Cells, Nat. Prod. Res., 2006, 18: 760．

[5] Wei-juan Dai, Duan-yun Si, Shao-hong Wang et al., Effects of Polysaccharide of Ficus carica on Immunologic Function of Tumor-loading Mice, Lishizhen Medicine and Materia Medica research, 2001, 12 (12): 1059．

[6] Wei-juan Dai, Duan-yun Si, Qin Xin et al., Effects of Fices carica Polysaccharides on immunologic Function in Mice, Journal of Chinese Medicinal Materials, 2000, 31 (5): 355．

[7] Wei-juan Dai, Duan-yun Si, Wei-fa Zhong et al., The FCPS right mouse mononuclear phagocyte function investigation, Chinese Archives of Traditional Chinese Medicine, 2002, 20 (1): 98．

[8] Dong-ju Sun, De-ling Huang, Zhao-qiang Zhang, Experimental Study of the Anti-Fatigue and Hypoxia Tolerance Function of Fig Extract on Rats, Occup Health, 2007, 23 (13): 1105．

[9] Zhao-qiang Zhang, Chun-zhi Zhang, Li Lin, The effects of the water extract of F icus Carica on anti-fatigue and NOS activity, Chinese Journal of Behavioral Medicine Science, 2006, 15 (9): 783．

[10] Zhao-qiang Zhang, Chun-ji Han, Dong-ju Sun, The Antigonism Effect of the Water Extract of Ficus Carica Against CP- induced Micronuclei, Journal of Jining Medicine College, 2003, 29 (3): 15．

[11] USDispensatory. 24Ed. 1947: 1455.

[12] Zong-you Li, Foreign Medical Sciences. Chinese medicine Chinese medicine Volume, 1992, 14 (1): 55.

[13] Chennongshangcilang, Medical Central magazine (Japanese), 1965, 206: 636．