1 Cardiac function：When squeezed the juice filtrate dropping saxifrage or 1:1 ethanol extract 0.01ml to the isolated frog heart, it shows certain cardiac function. The calcium-free extract still has excitatory effects on heart, while the effect is weaker than calcium-contained extract. The cardiac function of this product is slower compared with calcium oxide and has longer duration [1].

2 Antibacterial activity: The ethanol extract of Saxifrage can inhibit the growth of Staphylococcus aureus, Bacillus thuringiensis, Escherichia coli and Bacillus subtilis [2].

3 Diuretic activity: Anesthetized dogs and conscious rabbits intraperitoneal injection of 1ml/kg saxifrage ethanol extract, can exhibit obvious diuretic effect. After the destruction of the glycosides contained in the extract, there is still some diuretic effect [1].

4 Induction of apoptosis: Saxifrage ethanol extract can inhibit the proliferation of rat fibroblasts [3] and human prostate cancer cell [4] in vitro, and induce apoptosis.

Prostatic hyperplasia: 32 cases were treated with Preparation of, 13 cases of them were treated with “Herba Saxifragae Injection” via perineum prostate, 2ml each side, one time every 5-7 days, 10 times for a period of treatment; 8 patients of them were treated with “Herba Saxifragae Suppository” via rectally, one time a day, 3 months for a period of treatment; 11 cases of them were treated with “Herba Saxifragae Injection” via perineum prostate and “Herba Saxifragae Suppository” via rectally. Results: Four observation indexes before and after treatment were significant difference (P<0.01 or P<0.05)^[1].

1.Chilblain with ulcer

2.Hemorrhoid

3.Vomiting smelly pus caused by abscess of lung

4.Hematemesis

5.Urticaria due to toxic heat, toothache due to wind-fire

6.Urticaria

7.Rubella with itching, eczema

8.Metrorrhagia

Chemical composition：

[1]Luohouwei, Weibaojin, Chenjieyan, etal. Study on the effective constituents of Saxifraga stolonifera. Journal of China Pharmaceutical University. 1988,19(1):1.

Pharmacological effects：

[1]Nanjing University of Chinese Medicine. Chinese Dictionary. Second Edition(The first volume). Shanghai: Shanghai Science and Technology Press, 2006:1876.

[2]LIU Shi-wang,XU Yan-xia. Inhibition Effect of Ethanol Extract of Saxifraga stolonifera Meerb. on Microorganisms. Resource development market ,2007,23(6):481.

[3]Zhanglishi, Dingjiaxin, Zhangqiuhai, etal. Saxifrage extract on rat fibroblast cell inhibition. China Journal of Basic Medicine In Traditional Chinese Medicine, 2005,11(l2):920.

[4]Dingjiaxin, Zhanglishi, Zhangling. Ear grass extract on prostate cancer cells apoptosis. China Journal of Basic Medicine In Traditional Chinese Medicine, 2005,11(12):905.

Clinical reseach：

[1]Jun LongTao. The clinical effect of Saxifrage preparations on prostate hyperplasia[J]. Chinese Journal of Basic Medicine in Traditional Chinese Medicine .2007, 19 (1) : 79.

toxicology：

[1]Nanjing University of Chinese Medicine. Chinese Dictionary. Second Edition(The first volume). Shanghai: Shanghai Science and Technology Press, 2006:1876.