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[English Name] Common Knotweed Herb
[Chinese Name] 萹蓄  
[Pinying Name] Bianxu  
[Latin Name] Polygoni Avicularis Herba  
[Genera] Polygonaceae
[Efficacy] Damp-clearing drug
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology] It grows in field and road side.  
[Chemical composition]

This plant contains flavonoid: avicularin, vitexin, quercitrin, luteolin, quercetin, isovitexin, rhamnetin-3-galactoside, hyperin[1];

coumarins: umbelliferone, scopoletin[1];

acidic component: sinapic acid, vanillic acid, ferulic acid, syringic acid, melilotic acid, p-coumaric acid, p-hydroxybenzoic acid, gentisic acid, caffeic acid, catechin, protocatechuic acid, ellgaic acid, p-hydroxyphenyl acetic acid, chlorogenic acid, salicylic acid, ellagic acid, oxalic acid, silicic acid[1];

saccharide: glucose, fructose, sucrose, water-soluble polysaccharide[1];

amino acids: methionine, proline, serine, threonine, tyrosine, phenylalanine, cystine, arginine, valine, glycine, leucine, lysine, isoleucine, tryptophan[1].

 
[Pharmacological activities]

1. Diuresis: Water extract show strong diuresis action on rat[1,2]. The activity compound may be its sylvine[3]. Avicularin show diuresis action on rat and dog when it used as intravenous injection[4].

2. Lowering Blood Pressure: Armstrong extract show lowering blood pressure activity on cat, dog and rat model through noncompetitive inhibit angiotensin converting enzyme[4-6].

3. Antibiosis: Armstrong can inhibit the growth of bacillus dysenteriae, ringworm fungus and microsporon lanosum[7-9].

4. Other Effects: Armstrong still has raise breathing exercise, hemostasis with astringents, cholaneresis, potentiated carboxypeptidase activity[6,10]. Luteolin, Vitexin and its glycoside can inhibit human platelet aggregation[11].

 
[Clinical trial]  
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]  
[Toxicological studies]  
[Pharmaceutical preparations]  
[References]

Pharmacologic Actions:

[1] Haverland F. C A, 1964,61:7362a.

[2] Huang Houpin, Cheng Caifen. Journal of Guiyang Medical College,1963,(0):36.

[3] Lv Xianghua. Acta Pharmaceutica Sinica, 1966,13(6):454.

[4] Li Yunshan, Fu Shaoxuan, Han Rui, et al. Acta Pharmaceutica Sinica, 1959,(01):1.

[5] Aluf M A. C A, 1946,40:5844.

[6] Inokuchi J. C A, 1985, 102:197701h.

[7] The Clinic Internal Medicine Teaching and Research Group of Hunan Meidical University Journal of Central South University(Medical Sciences), 1959,(04):63.

[8] Gao Jie. Chinese Journal of Postgraduates of Medicine, 1980,(7):18.

[9] Zheng Wufei. National Medical Journal of China, 1952,38(4):315.

[10] The new Jiangsu School of Medicine. Grand Dictionary of Chinese Medicine(the last volume, 1st edition), Shanghai: Shanghai Science & Technology Press, 1977:2329

[11] Pahosyan A . Khim-Farm Zh, 1986, 20(2) :190 (C A, 1986,104:199798k ).

[12] Wan J M. Medicinal and Poisonous Plants of Southern and Eastern Africa Zed.1962:859.