Yerbadetajo Herb - China and Thailand medicinal plants professional database

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[English Name]	Yerbadetajo Herb
[Chinese Name]	旱莲草
[Pinying Name]	Hanliancao
[Latin Name]	Ecliptae Prostratae Herba
[Genera]	Compositae
[Efficacy]	buyao
[Pictures]	Plant picture	Drug picture

[Alias]
[Source]
[Plant morphology]
[Distribution]
[Gathering and processing]
[Characteristics]
[Ecology]	It prefers grows in wet area,can be seen in road side、field side、pond side and river bank,and also in wet waste land or waste paddy field.It has strong ability of shade resistance,can grows well in dank land.It doesn’t resistant to drought,plant is short and grows unwell in slightly droughty land.
[Chemical composition]
[Pharmacological activities]	1. Bacteriostasis and Dephlogisticate: Yerbadetajo show bacteriostasis activity on staphylococcus aureus, bacterium typhosum, bacillus dysenteriae and aeruginosus bacillus[1]. Water extract show anti-inflammatory action on mice and rat model and this effect did not depend on adrenalin[2]. 2. Hepatoprotection: Yerbadetajo 50%e thanol and acetic ether extract show strong protective effect on hepatic injury induced by carbon tetrachloride and paracetanol on rat and mice[3,4]. 3.Effect on Immune Function: Water extract can obviously enhance specific immunity and cellular immune function and without effect on humoral immunity on mice[5,7]. Both 20% diluted alcohol extract and compound S₂,S₃and S₈can enhance lymphocyte activity[6]. Eclipta acetic ether extract show immunoloregulation action on cellular immunity[8-11]. 4. Effect on Thymus Cell: Water extract inhibit mice thymus cell apoptotic induced by cyclophosphamide[12]. 5. Anti Mutagenesis: Water- soluble extractive inhibit erythrocytes micronucleus induced by cyclophosphamide[13]. 6. Effect on Cardiovascular System: Eclipta show protect effect on coronary heart disease in vivo and vitro[14]. 7. Hemostasis: Eclipta powder and water extract show hemostasis activity on dog bleeding wound and mice excessive heat gastric bleeding[1,15,16]. 8. Anti-Oxidant and Stay Caducity: Eclipta extract can enhance superoxide dismutase, glutathion peroxidase, Na⁺-K⁺-ATP and Ca²⁺-ATP enzyme activity and cut down malondialdehyde content through scavenge free radicals[17-21]. And it can enhance learning and memory ability and increase the hypoxia tolerance on mice[19,22]. 9. Other Effects: Eclipta show anticancer^[1], sedative, analgesia^[14] and detoxication activity also[23].
[Clinical trial]	1. Flat wart: the treatment group of 60 cases were givenHanliancao(Yerbadetajo Herb ), Zhima every 30 g, to extract by boiling water,for wash affected area outside, wash with gauze swab repeatedly, 15 ~ 20 minper time, 2 times per day, 1 agent per day, 15 d as one period of treatment.Results:in treatment group 36 cases were cured, 17 cases were markedlyimproved, while 3 cases were better and 4 cases were invalid, the cure ratewas60%, the total effective rate was 88.33%^[1]. 2. Alopecia areata: Hanliancao (Yerbadetajo Herb ) 20 g per day, 6 ~ 10times per day, 2 weeks as one period of treatment. The 26 cases for 1 month oftherapy, 16 cases were cured, 5 cases were markedly improved, 3 cases wereeffective, 2 cases were invalid^[2].
[Properties]
[Medical and other Uses]
[Dosage]
[Cautions]
[Traditional usage]
[Toxicological studies]
[Pharmaceutical preparations]
[References]	Pharmacologic Actions: [1] Chen Keji. Stay Caducity Chinese Materia Medica. Beijing: Chinese Ancient Books Publishing House, 1989:289. [2] Hu Huijuan, Zhou Derong, Hang Bingqian. Journal of China Pharmaceutical University, 1995,26(4):226. [3]Bupinder Singh. International Journal of Traditional Chinese Medicine, 1991,13(6):29. [4] Li Chunyang, Bai Xiuzhen, Yang Xuedong. Journal of Mathematical Medicine, 2004,17(3):249. [5] Hu Huijuan, Hang Bingqian, Liu Yong. Journal of China Pharmaceutical University, 1992,23(1):55. [6] Zhang Mei, Chen Yayan. Journal of Beijing Medical University, 1994,26(5):330. [7] Feng Minggong, Cai Ying, Chen Qun. Journal of Dalian University, 1999,20(4):74. [8] Qin Hua, Liu Mei, LiuXueying, et al. Shaanxi Journal of Traditional Chinese Medicine, 2002,23(1):73. [9] Liu Xueying, Wang Qingwei, Zhao Yueping, et al. Chinese Traditional Patent Medicine, 2001,23 (1):43. [10] Liu Xueying, Zhao Yueping, Jiang Yongpei, et al. Academic Journal of Fourth Military Medical University, 2001,22(8):754. [11] Wang Yiwei, Zhou Qingfeng, Bai Xiuzhen. Journal of Jinzhou Medical College, 2003,24(6):28. [12] Jing Hui, Bai Xiuzhen, Yang Xuedong, et al. Journal of Mathematical Medicine, 2005,18(4):318. [13] Weng Yufen. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 1993,(1):55. [14] Zhou Yuebo, Li Yunzhong, Zhang Suying, et al. Tianjin Medical Journal, 1986,14(8):490. [15] Takuo Kosuge. Journal of Pharmacy(Japan), 1981,101(6):501. [16] Wang Jian, Bai Xiuzhen, Yang Xuedong. Journal of Mathematical Medicine, 2005,18(4):375. [17] Li Ge, Zhou Lin, Yang Fengyun. Journal of Shanxi Medical University, 2005, 36 (5) :574. [18] Zhang Yaofeng, Chen Li. Academic Journal of Fourth Military Medical University, 2006, 27(10) :957. [19] Hao Hong, Yuan Yao. Journal of Chengdu University of Traditional Chinese Medicine, 2007, 30(1):25. [20] Lin Chaopeng, Rui Hanming, Xu Xiaochun. Military Medical Sciences, 2005,29(4):344. [21] Shi Bianhua, Zhuang Xiaoyan, Bai Xiuzhen. Journal of Mathematical Medicine, 2007,20(2):208. [22] Zhu Yuyun, Jiang Longmei, Zhang Feng, et al. China Journal of Clinical Rehabilitation, 2005,9(24):168. [23] Singh B. International Journal of Traditional Chinese Medicine, 1994,16(2):101. Clinical trials: [1] CHANG Shuling. Theobservation on Hanliancao and Zhima for treatment of Flat wart in 60 cases. TheJournal of Medical Theory and Practice,2004,17(6):680. [2] WU Rui,XU Huaqing,GUO Hongmei.Hanliancao for treatment of Alopecia areata. Modern Journal of IntegratedTraditional Chinese and Western Medicine,2000,9(10):950.