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[English Name] Medicine Terminalia Fruit
[Chinese Name] 诃子  
[Pinying Name] Hezi  
[Latin Name] Chebulae Fructus  
[Genera] Combretaceae
[Efficacy] shouseyao
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]     It grows in open froestapricus hillside at the altitude between 800 to 1800 metres.  
[Chemical composition]  
[Pharmacological activities]

 

 
[Clinical trial]

1. Child cough22 cases of patients treated with hezisanao decotion (hezi(Medicine Terminalia Fruit), mahuang(ephedra), xingren(almond), gancao(radix glycyrrhizae)).Results showed that in 3 days, 13 cases symptoms disappeard,9 cases had relived . when compared to the control group(no hezi(Medicine Terminalia Fruit), Other same),Two groups had Statistically significant difference(P<0.05) [1]

2. Chronic paronychia56 cases were treated with dahuanghezi mixture (dahuang(rhubarb), hezi(Medicine Terminalia Fruit), Danshen(Salvia Miltiorrhiza Bge) ) for external use. Results showed that the overall effective rate was over 98.2%, The time taking drugs last from 3 days to 17 days, the common time last 56 days[2]

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]

1. Heat and wind going upward

2. Reddish eyes with pain, hottish epiphora and dryness in eyes

3. Ulcer and soreness around lips

4. Unhealed aphthae

5. Ecthyma

6. Unhealed ingrowing nail with suppuration

7. Infantile chronic dysentery with rectal prolapse

8. Frequent urine, enuresis, frequent tears or mucus or salivation in the aged caused by qi deficiency

9. Aphonia

10. Unstopped hemoptysis caused by impairment of lungs

11. Loss of essence due to kidney deficiency

12. Used in the final period of abdominal pain and diarrhea

13. Chronic rectal prolapse combining carneous diarrhea with more white pus and tenesmus

14. hemafecia due to wind toxin in intestines

15. Vomiting, fullness in chest and anorexia caused by postpartum stomach deficiency

 

 
[Toxicological studies]  
[Pharmaceutical preparations]  
[References] Pharmacological actions:

[1] Cheng HY, Lin TC, Yu KH, et a1.Antioxidant and free radical scavenging Activities of Terminalia chebula. Biol Pharm Bull, 2003 ,26(9):1331-1335

[2] Saleem A, Ahotupa M, Pihlaja K. Total phenolics concentration and antioxidant potential of extracts of medicinal plants of Pakistan. Z Naturforsch C, 2001,56(11-12):973-978.

[3] Naik GH, Priyadarsini KI, Satav JG, et al. Comparative antioxidant activity of individual herbal components used in Ayurvedic medicinePhytochemistry, 2003,63(1):97-104.

[4] Malekzadeh F, Ehsanifar H, Shahamat M, et al. Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori. Int J Antimicrob Agents, 200l,l8(1):85-88.

[5] Sato Y, Oketani H, Singyouchi K, et al. Extraction and purification of effective antimicrobial constituents of Terminalia chebula RETS. against methicillin-resistant Staphylococcus aureus. Biol Pharm Bul1,1997,20(4):401-404

[6] Ahn MJ, Kim CY, Lee JS, et a1. Inhibition of HIV-1 integrase bygalloyl glucose from Terminalia chebula and flavonol glycoside gallates from Euphorbia pekinensis. Planta Med, 2002, 68(5):457-459.

[7] Saleem A, Husheem M, Härkönen P, et al. Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit. J Ethnopharmacol, 2002,81(3):327-336.

clinical test:

[1] Zou yongxiangzhao pengjun. Clinical observation on hezisanao decotion treated with hezisanao decotion in 32 casesJournal of Luzhou Medical College199619(6)

[2] Ling lijun gong guoying. Chronic paronychia treated with dahuanghezi mixture in 56 cases,Jiangsu Journal of Traditional Chinese Medicine199920(9)24.