| [English Name] | Pale Butterflybush Flower Bud | |
| [Chinese Name] | 密蒙花 | |
| [Pinying Name] | Mimenghua | |
| [Latin Name] | Buddlejae Flos | |
| [Genera] | Loganiaceae | |
| [Efficacy] | Antipyretic drug | |
| [Pictures] | Plant picture | Drug picture |
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| [Plant morphology] | ||
| [Distribution] | ||
| [Gathering and processing] | ||
| [Characteristics] | ||
| [Ecology] | It’s flowering phase is from February to March, fruiting phase is from July to August.It grows in hillside, hardwood forest,river side and hilly country,commly grow in semi-shade. | |
| [Chemical composition] | ||
| [Pharmacological activities] |
1.Effect on Hepatic: Water extract of flower inhibit cytotoxin induced by hepatocyte in vitro. And buddleo-glucoside was the activity compound[1]. But root water extract show no hepatic protection in hepatic injury rat induced by carbon tetrachloride[2]. Acacetin can shortening sleeping on hepatic injury rat model induced by carbon tetrachloride[3]. 2.Other Effects: Robinin contains in buddleja offiginalis possess anti-inflammatory, spasmolysis and cholaneresis activity[3]. Butanol-extractable materials can decrease blood sugar level on diabetes rat model[4]. Hormonelike Activity: Extract can significant inhibit xeroma development on rabbit model induced by androgen[5]. Water extract show a immunoloregulation activity on immunosuppression mice induced by cyclophosphamide[6]. |
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| [Clinical trial] | Mimenghua (Buddleja officinalis) 1 conjunctivitis : Compound miming(buddleua officinalis) flowersoup (basic compose: miming flower(Buddleja officinalis) 30g, longdan grass(Gentian)10g, fangfeng(hurricane lamp) 20g, niubangzi(Great Burdock Achene) 15g, jingjie(Schizonepeta)10g, qianhu(Peucedanum) 15g, huanglian(Coptis chinensis) 10g, tianhuafen(radicestrichosanthis) 20g, baishao(white paeony root) 20g, juhua(Chrysanthemum) 10g,shijueming(concha haliotidis) 20g, jinyinghua(honeysuckle) 20g) to treat 30 diagnosedcases, daily 1 agent,1-3 times a day. Results: 25 cases were cured, 4 casesimproved, 1 case invalid, the total effective rate was 96.7% [1]. 2 Pediatric eye blink : self-made mimeng flower powder (mimingflower(Buddleja officinalis), huangqin(Scutellaria) 8-10g respectively, jingjie(Schizonepeta),changzhu(rhizome atractylodis), heidou(Black soya bean), sangye(Mulberry leaves),heshi(Lappula Myosotis), binglang(Betel nut), cishao(Red peony root), 6-8grespectively, danggui(Chinses Angelica), chantui(Cicada slough) 4-6grespectively, gancao(Licorice root) 4g), take 3-5 times a day, 4 agent acourses. 8 cases were cured at 1 course, account for 4%; 174 cases were curedat 2 courses, account for 87%; 18 cases were cured in 3 courses, account for9%. Follow up 6 months to 2 years, 6 cases recurrence, after 2-3 courses oftreatment, followed up for 3 years without recurrence [2]. |
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| [Properties] | Taste: sweet; property: slightly cold; belong to liver channel. |
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| [Medical and other Uses] | Function: expelling wind and clearing away heat, moistening liver and improving acuity of sight, removing nebula. Syndromes to be treated: conjunctive congestion with swelling and pain, photophobia, macula or leukoma of cornea, blurred vision. |
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| [Dosage] | Oral administration: decoction, 3～ |
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| [Cautions] | Forbid to be used in the patients with the syndrome inclding hepatic cold and stomach weakness, deficiency of internal injuries, Workers injured eye disease. |
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| [Traditional usage] | 1.Ulcer on eyes with profuse tears 2.Photophobia 3.Blindness due to infantile malnutrition 4.Eyes problems, frequent use of eyes leading to distention, swelling, pain and blindness 5.Night blindness 6.Visual deterioration due to liver deficiency 7.Dim sighted, photophobia with secretion and tears, hordeolum, difficulty with opening, itching or pain, blurred vision induced by nebula, eye pain caused by chronic headache, dim sighted with swelling and pain 8.Cataract | |
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| [References] |
Pharmacologic Actions: [1] Houghton P J, et al. World Phytomedicines, 1990,5(4):178． [2] Jin Ling, Zheng Zimin, Qin Daoguang, et al. Journal of [3] The new Jiangsu School of Medicine. Grand Dictionary of Chinese Medicine(the last volume, 1st edition), Shanghai: Shanghai Science & Technology Press, 1977:2264． [4] 2008,39(1):87．Li Haidao, Feng Suxiu, Ye Ru, et al. Chinese Traditional and Herbal Drugs, 2008,39(1):87． [5] [6] Wu Kefeng, Liu Jia, Yu Hong. Journal of Guiyang Medical College, 1997,(4):359． [1] JinShuSen. Compound miming flower soup treatment conjunctivitis30 cases. Yunnan TCM magazine, 1998, 19(1):21. [2] ChenZhaoMing. The selt-mademiming flower scattered in treating pediatric eye blink. Yunnan institute oftraditional Chinese medicine journal, 1999, 22(2):39. |
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