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[English Name] Cockscomb Flower
[Chinese Name] 鸡冠花  
[Pinying Name] Jiguanhua  
[Latin Name] Celosiae Cristatae Flos  
[Genera] Amarantaceae
[Efficacy] zhixueyao
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]     It prefers enough sunshinemoist and hot,doesn’t resistant to frost and infertility,prefers loosefertile and well-drained soil.  
[Chemical composition]  
[Pharmacological activities]

1. Preventing fluoride toxicity: the food supplemented with calcium can reduce the effect of high fluorine, and the food supplemented with both calcium and Celosia Cristata extracts is better[1].

2. The water extract of Celosia Cristata could enhance immune function of mice[2].

3. Celosia cristata has the obvious haemostatic effect and its haemostatic mechanism is related to its rich content of Ca2+ and Vitamin C[3,4].

4. Celosia cristata has the anti-aging effect on mice induced by D-galactose[5].

5. Celosia cristata could strengthen the mouse endurance and increase the deposit of muscle glycogen and hepatic glycogen[6].

6. Atheroslerosis: The ethanol extract of Celosia cristata possesses the actions of lowing lipids and MDA and may prevent fatty liver[7,8].

7. The water extract of Celosia cristata exhibits a killing effect on Trichomonas vaginalis[9].

8. Celosia cristata injection exhibits obvious effect of inducing abortion in second trimester on pregnant mice, guinea pig and rabbit[10].

 
[Clinical trial]

1. Leukorrheal diseases due to heat-toxicity: jiguanhua (Cockscomb Flower) mixture in treating several hundred patients, all obtained remarkable curative effect. Oral prescription ( carbon red jiguanhua (Cockscomb Flower) 30g, fried gluten white jiguanhua(Cockscomb Flower) 30g, baizhu(Atractylodes macrocephala koidz) 20g, baijiangcao(Patrinia) 20g , pugongying(Mongolian Dandelion Herb)20g, yuxing cao(Heartleaf Houttuynia Herb)20g, chishao ( red Herba Peony)10g ,baitouweng(the root of Chinese pulsatilla )20g, gualou(snakegourd fruit) 20g ); the external prescription ( sheng white jiguanhua (Cockscomb Flower)50g,shechuanzi(Common Cnidium Fruit) 30g , yaozhuxiao(Paniculate Swallowwort Root) 20g)for washing vulvar , 1 agent daily).Results showed that it had good effect after 35 agent generally [1].

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]

1.Rectal prolapse with bleeding

2.incessant menorrhea

3.Morbid leucorrhea, urolithic stranguria

4.Leucorrhea with red and white discharge

5.Morbid leucorrhea due to weakness

6.Infantile hemorrhoids bleeding and dysentery with bloody stool

 
[Toxicological studies]  
[Pharmaceutical preparations]  
[References] Pharmacological actions:

[1] Li Wan-li,Yuan Zhi-qing et al. Effect of calcium and cristata L extracts on bone mineral densit and urinary mineral of rats. JOURNAL OF HYGIENE RESEARCH, 1999,28(4):230-231.

[2] CHEN Jing, WU Feng-lan, ZHANG Ming-zhu, et al. Effect of cristata L on immunologic function of mice. Chinese Journal of Public Health, 2003,19(10):77.

[3] CHEN Jing, JIANG Xiu-mei, LI Tan, et al. Research of Haemostatic Effect Mechanism of Celosia cristata. JOURNAL OF BEIHUA UNIVERSITY(NatttraI Science), 2001,2(l):39- 40.

[4] GUO Li-wei, YIN Fei, WANG Tian-shan, et al. Haemostatic Effect and Its Mechanism of Celosia cristata. Journal of nanjing university of Chinese medicine, 1996,12(3):24-26.

[5] CHEN Jing, LIU Ju-sen, WU Feng-lan, et al. Effect of Celosia cristata on ageing mice induced by D-galactose. Chinese Journal of Gerontology, 2003,23(10):687-688.

[6] CHEN Jing, Li Tan, Jiang Xiu-mei, et, a1. Experimental Research of Celosia cristata on the Mouse Endurance. Lit & Inf Prev Med, 2000,6(2):109-110.

[7] LI Wan-li, ZHANG Zhi-sheng, ZHOU Yun-zhi, et al. The efeets of Taurine and alcohoI extraction of Cristata L on Blood lipids and M DA in rats. Journal of Xinxiang Medical College, 1996,l3(4):338-341.

[8] TIAN Yu-hui, LI Wan-li, XUE Ying-chun, et al. Effects of ethanol extract of Celosia cristata on Xn, Cu, Fe, and Ca of rats raiseed with high fat food. Modern Rehabilitation, 1998,2(2):92-93.

[9] ZHAI Tian-qi, ZHU jing. Effect of 120 chinese herbs on killing trichomonas vaginalis. Tianjin Medical Journal, 1978,(5):207-209.

[10] QIN Bai-xuan, YAN Yi, LI Ping. Study on medium induction of Celosia cristata. Journal of Chinese patent drug research, 1987,(8):39.
clinical test:

[1]Tan yongai. leukorrheal diseases due to heat-toxicity treated with national medicine jiguanhua (Cockscomb Flower) mixture.Chinese national medicine.2007,(2):7.