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[English Name] Japanese Hop Herb
[Chinese Name] 葎草  
[Pinying Name] Lücao  
[Latin Name] Humuli Scandentis Herba  
[Genera] Moraceae
[Efficacy] Antipyretic drug
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]     It grows in ditch sideroad side and wasteland.  
[Chemical composition]  
[Pharmacological activities]

1 Antibiosis: The stems, leaves ethanolimmersion significantly inhibited Gram-positive bacteria [1]. Lupulone andhumulone significantly inhibited the gram-positive bacteria such asStaphylococcus aureus, Streptococcus faecalis, Streptococcus pneumoniae,diphtheria bacillus, Bacillus anthracis, Bacillus subtilis and cereus bacteria.Lupulone antimicrobial concentration between 1:100000-1:1000000, the humulone hadweak inhibitory effect [2,3], lupulone inhibitory concentration ofMycobacterium tuberculosis is 25μg/ml [4]. The lupulone can decrease the numberof acid-fast bacilli within the lesions of the liver, heart, lung and spleen[5].

2 Immunopotentiation activities: the extractsfrom Humulus.Scandens obviously enhanced leucocyte phagocytosis, thesterilizing ability and lysozyme activities in grass carp blood [6].

3 Acute renal failureeffects: Humulus scandens Merrcould significantly increase the urination function, decrease serum levels ofBUN and Scr, ameliorate the electrolyte, and has therapeutic action on CRF inrats [7].

4 The others: the humulone haddinitrophenol effects on the cat, after the intravenous injection 3mg/kg, oxygenconsumption immediate increased, shortness of breath, following elevating bodytemperature may be due to the excessive rise in body temperature (45 ° C) anddeath. Large number of injections can produce glycosuria, hematuria [1]. Humulusalcohol extract has a significant role in promoting the growth of grass carp[8].

 
[Clinical trial]

Lvcao (scandenthop)

1. infantile diarrhea: (1)in treating pediatric autumn diarrhea give scandenthop anointed applyumbilical, 24 hour change medicine, 3 times the normal shit until row, stopdressing. 100 cases of treatment, after 72 hours treatment group significantefficiency is 56%, compared with the control group think secret (significantefficiency is 16%), the efficiency rate of the 2 groups has significantlydifferent (P<0.01) by statistics processing[1]. (2) The treatmentof noninfectious infantile diarrhea: 200 cases were randomly divided into twogroups, 100 cases in each group, all use bowel mucous protective agent simidaand help intestinal resume normal flora ecological equilibrium mommy loveconventional oral. On this basis, the treatment group accept scandenthop Friedliquid immersion foot (fresh scandenthop 500g or dry scandenthop 250g add water1000 mL, soft fire boil 10 min and cool to 40℃, soak feet into the solution 10-15min,twice a day,3 days for a period of treatment, determine efficacy after acourse). Results: the cure rate of treatment group was 78% and 56% in controlgroup, there was a significant difference in the 2 groups (P<0.05) [2].

2.Shingles: Clean and dry the raw product, pound the fresh, take the juice. Witha sterile cotton dips in medicine juice besmear rod can be affected, 5-6 timesper day. 21 cases treatment, have been markedly improved [3].

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage] 1.Skin Itching 2.Infantile pemphigus 3.Reddish and swollen joints with heat and pain 4.Scrofula 5.Pulmonary tuberculosis 6.Typhoid fever after sweating 7.Acute and chronic malaria 8.Urolithic stranguria 9.Stranguria due to chyluria 10.Hemorrhoid with rectal prolapse  
[Toxicological studies]  
[Pharmaceutical preparations]  
[References]

Pharmacology Actions:
[1]
Jiangsu new medical school. Chinese medicine (next volume). To the first edition. Shanghai science and technology publishing house, 1977: 2313

[2] Salle A J.Proc Soc Exp Biol Med, 1949, 70: 409.

[3] Lewis J C. J Clin Invest, 1949, 28(5): 916.

[4] Yin-Chang Chin. J Clin Invest, 1949, 28 (5): 909.

[5] Yin-Chang Chin. Proc Soc Exp Biol Med, 1949, 70: 158.

[6] Lai-ting Liu, Hui-ru Zhang, Jian-xin Feng et al., Humulus alcohol extract on the grass carp non-specific immune function, Chinese Journal of Animal Science, 2008, 44 (9): 29-31.

[7] Yu-juan Zhou, Li Liu, Shao-qing Li et al., Experimental Study of Humulus decoction for treatment of acute renal failure, Journal of Chinese PLA Postgraduate Medical School. 2007, 28 (04): 287.

[8] Lai-ting Liu, Hui-ru Zhang, Qie-gang Ma et al., Humulus alcohol extract of grass carp growth performance, Journal of Henan University of Technology(Natural Science Edition), 2008, 29 (02): 27.
Clinical experiment
 
[1] Wang guoyan, Cai xinsheng, Zhu yanmei, etc. The curativeeffect observation of lvcao treatment 100 pediatrics autumn diarrhea. NewTraditional Chinese medical science, 2000, 32(1):15.

[2] Li qinkuan, Lixihua, Liang hongwen, etc. lvcao decoction immersion foottreatment of infantile diarrhea noninfectious 100 cases. The Chinese practicalrural doctors surg, 2005, 49 (8): 41-42.

[3] Liu hanliu. Lv Grass  treatment of herpes zoster. Jilin Chinese medicine, 1994 (4) :52.