1. Anti Bacterial Endotoxin: Nanshele extract can inhibit tachypleus amebocyte lysate aggregation induce by 20 times dose bacterial endotoxin[1].

2. Anti-Cobratoxin Action: Nanshele extract can inhibit tachypleus amebocyte lysate aggregation induce by 10 times dose cobravenom[2].

Kushilian (Seed of WhiteflowerCacalia)

herpes zoster: all cases, 45 male and 48female, aged 17- 78 years old, the course of 1 -5 days, the control group: acyclovir 200 mgoral, 5 times/day, last for 10 days. The treatment group:acyclovir usage with the control group, 180g nanshele(Caesalpinia minaxHance), add 1000 ml waterdecoct 2 times to 500 ml. wash 2-3 times every day (inflammation obvious personwith decoction wet apply), treatment 10 days. Two groupsat the same time use the calamine lotion outside. Results: treatment group symptoms improve timethan control group were obviously reduced. A treatment for 10 days, the curerate of treatment group was 63.4% and significant efficiency than the controlgroup(33.3%) were obviously improved, 30 days, the treatment group (5 patientssuffered from postherpetic neuralgia, and the incidence rate is 5/93), acyclovir group（13 patients suffered from herpes zoster postherpetic neuralgia, and the incidence rate is 13/87）. Two groups had significantdifference (P < 0.05). During the washing with Caesalpinia minax Hance, adverse reactions were not found ^[1].

1.Ulcer and sore, venomous snake bite

2. Edema of excess type

[1] Luo Zhihua, Zhang Jianmin, et al. China Medical Herald, 2006,3(30):148．

[2] Li Jingxin, Jiang Sanyuan, Tang Rongde. Journal of Snake, 2006,18(2):96．
clinical experiment

[1] Ye Huanyou, Tang Rongde, Jiang Sanyuan etc. The clinical observationof nanshele treatment herpes zoster. China integrated traditional Chinese andwestern medicine in skin venereal res, 2005, 4 (2): 105.