1 Cholagogueeffect: Yinchenhao 6,7-dimethoxy coumarin hydroxyacetophenone and chlorineacid, beta-pinene, capillaris ketones, folic acid etc. had choleretic effect [1,3].YinChendecoction, hot water extract, the infusion of volatile oil and water, etc. canalso promote the secretion of bile and excretion effects [2].

2 Protectionliver: YCHT has hepatoprotective effect withdose-effect relationship and its mechanism may relate to reducing thehepatocyte content of β-G, promoting the excretion of bilirubin and improvingthe metabolism of bilirubin. The extracts of Swertia musstii Franch(10μg/ml, 1μg/ml,10-1μg/ml, 10-2μg/ml) could reduce the levels of AST, ALT, LDH and MDA incultural supernatant which reduced by CC1₄. It also could boost thehepatocytes viability which reduced by CC1₄. The results suggestthat polysaccharides from Swertia musstii Franch have direct protectiveactivity on hepatocytes injured in vitro [4,5].

·        3 Immunologic function: The Yinchenhao can promote leukocyte split,increase the number of white blood, increase the activity of T cell immunity,and participate in the role of immune regulation and induce interferon, andthus improve immune function [6]

4 Heart-blood vesselsystem: Artemisia capillaris thumb showed in different degree effect on theregression of coronary arteries atherosclerosis and aortic atherosclerosis(p<0.01) and on the expression of oncogenes (p<0.01). These medicinesshowed an excellence in antiatherosclerosis 6,7-dimethoxy-coumarin[7].

5 Antipyretic,analgesic and anti-inflammatory: Artemisia coumarin had analgesic effect [6].6,7-dimethoxycoumarin had anti-inflammatory effects on rat paw swelling,significant cooling effect on body temperature of normal mice and have asignificant cooling effect [8].

6 Anti-tumor:the capillaris inhibitory effect on lung cancer cells in vitro [9]. Yinchenhaocoumarins, terpenoids, flavonoids, coumaric acid, chlorogenic acid and otheringredients may have anticancer activity [10]. Yinchenhao decoction inhibit mousebone turn cell micronuclei, chromosome aberrations and sister chromatidexchange [11].

7 Anti-pathogenicmicroorganism: Capillaris had a strong anti-pathogenic microorganism effects. Yinchenhaodecoction had various degrees inhibition effects on the different bacterium. Itcan completely inhibit man-TB. Capillaris decoction can also inhibit and killBowmore Leptospira, pig and human roundworm has a narcotic effect [8]. All the12 diuretic traditional Chinesemedicines inhibited urogenital CT [12].

8 The others: Yinchenhaohad immunologicfunctionand dieresis effects [13,2].

1. Moderately severe acne：34 cases of patients were treated with oral administration of Fufang Yinchen decoction, twice a day, 4 weeks as one course of treatment. During the treatment, no other drugs were taken. Results: 20 cases were cured(49.02%), seven cases had significant effect(12.01%), four cases had effect(3.36%) and three cases were invalid, the effective rate was 91.18% ^[1].

2. diabetes type Ⅱ:40 cases of patients were treated with Jiaweiyinchen decoction and oral hypoglycemic drugs as the treatment group. Anther 40 cases of patients were treated with only the oral hypoglycemic drugs as the control group. Results: ①Compared the blood sugar before and after treatments, patients’ FBG had improved in both groups, but significant difference was obtained(P<0.05) when compared each other. The results of treatment group were better than the control group, which indicated that the better effect of reduce FBG can be obtain when Jiaweiyinchen decoction and oral hypoglycemic drugs were used together. ②Patients’TG had reduced significantly in both group, but no significant difference was found when compared each other (P>0.05) ^[2].

3. Cholelithiasis: 42 cases of patients were treated with herbs of Yinchen(20g), Shanzhizi(15g), Dahuang(10g), Jinqiancao(30g), Haijinsha(15g), Chenpi(30g), Chuanlianzi(10g), Baishao(15g), Zhike(10g), Gancao(6g). The herbs were extract by water, 5ml of pig's bile was added into. One month as a course of treatment. Results showed that 26 cases were cure(61.90%), 13 cases' condition had improved(30.95%), three cases were invalid(7.15%), the overall effective rate was 92.85%^[3].

4. Acute icteric hepatitis: Patients were treated with herbs of Yinchen, Zhizi, Huangqin, etc. medication time were about 13~66 days, and no side effect were found during the medication time. Results showed that 196 cases had significant effect, 32 cases' condition had improved, four cases were invalid, the overall effective rate was 98.3%^[4].

5. Vaginitis: Patients were treated with Yinchenhao decoction, one prescription were boiled each day and taken three times a day, ten prescription as one course of treatment. During the treatment, the traditional Chinese medical lotion were apply on the affect area, no other drugs were taken, and sexuality was forbidden. Results: 36 cases were cure(22.50%), 60 cases had significant effect(37.50%), 54 cases had effect(33.75%), ten cases were invalid(6.25%), the overall effective rate was 93.75%.

   Yinchen also have good effect for diseases such as spontaneous abortion of maternal-fetal blood group incompatibility^[6], eczema^[7], cholestatic hepatitis^[8], biliary ascariasis^[9], etc.

1.       Sweating on forehead and anidrosis on the body with the neck as the boundary, dysuria ,inclination to drink liquid when thirsty, stagnant heat inside and jaundice of the body of Yangming Syndrome 

2.       Jaundice with deep, string and slow pulse, cold limbs, spontaneous perspiration above the waist

3.       Jaundice with golden color, few words, weakness in the limbs, preferable to lie down and sleep, and spitting sticky fluid

4.       Varied infections of gallbladder

5.       Spots due to febrile disease

6.       Sweatstain

[1] Qing-ping Zhang, YCHT treatment of neonatal maternal and child blood group incompatibility hemolytic disease of 56 cases, Journal of Qiqihaer university of Traditional Chinese Medicine, 2002, 23 (1): 41.

[2] Jian-ya Zhou, Harvests of cotton capillaris and efficacy discussion, Journal of Jiangxi University of Traditional Chinese Medicine, 1996, 8 (4): 30.

[3] Zheng-yan Yang, The Chinese Physiological Society conference abstracts assembly (Pharmacology), Chinese Physiological Sciences publishing, 1964: 120.

[4] De-jiu Han, Chinese Traditional and Herbal Drugs communication, 1976, (8): 359.

[5] Yan-wen Liu, Journal of Chinese Medicinal Materials, 1994, 17 (6): 38.

[6] Ming-yan Zhe, Yi-qiao Hu, The Yinchenhao chemical and pharmacological research progress, Journal of Chinese Medicinal Materials, 1998, 29 (8): 564.

[7] Yong-hong Yu, Cang-xing Hu, Wei-xing Meng, Effect of Artemisia Capillaris Thunb, Radix Paeonia Rabrae, Spargrnium Stoloniferum Buch- Hum and Epimedium BrevicornumMaxim on Regression of Atherosclevosis and Expression of Oncogenes in Experimental Rabbiets, J Hubei Inst Nat I Med Edi, 2001, 18 (2): 4.

[8] Tian Xie, Xiao-qiao Niu, Zhan-bin Jiu, capillaris pharmacological effects and clinical advances, Journal of Heilongjiang University of Traditional Chinese Medicine, 2004, 4: 50.

[9] You-fan Jiang, The Effects of Capillarin on Proliferation and Cell Cycle of Lung Cancer Cell, China Pharmaceuticals, 2002, 11 (8): 30.

[10] Jie-yun Jiang, Journal of China Pharmaceutical University, 1992, 23 (5): 283.

[11] Zhen-feng Hong, Journal of Traditional Chinese Medicine 1992, 33 (8): 492.

[12] Jian-jun Li, Yu-ying Tu, Ju-zhen Tong, The 12-ingredient herbal diuresis medicine in vitro anti-active detection of urogenital Chlamydia trachomatis, Journal of Chinese Traditional Chinese Medicine, 2000,25 (10): 628.

[13] Wu TS. New constituents and antiplatelet aggregationand anti-HIV principles of Artemisia Capillaris, Bioorg Med Chem, 2001, 9 (1): 77．

Clinical trial:

[1]Li huaijun. Clinical Observation of Moderately severe acne Treatment by Fufang Yinchen decoction, Jilin Journal of Traditional Chinese Medicine, 2008,28(3):194.

[2]Yuan XiaoHan. Jiaweiyinchen decoction in Treatment of diabetes type Ⅱ in 40Cases. Traditional Chinese Medicinal Research, 2007, 20(2):43.

[3]Xu Jing. Jiaweiyinchen decoction in Treatment of Cholelithiasis in 42 Cases. Journal of Youjiang Medical College For Nationalities, 2005(4):575.

[4]Zhou XianWu. Jiaweiyinchen decoction in Treatment of Acute icteric hepatitis in 232 Cases. Shaanxi Journal of Traditional Chinese Medicine, 2008,29(1):78.

[5]Zhu Guang, Fei XinChao. Yinchen decoction in Treatment of Vaginitis in 160 Cases. Henan Traditional Chinese Medicine, 2008, 28(5):19.

[6]Han Pin. Analysis of Clinical Therapeutic Effect of Yinchen decoction in treating 132 cases of spontaneous abortion of maternal-fetal blood group incompatibility. Henan Traditional Chinese Medicine, 2008, 28(5):19.

[7]Ning Juan. Report of Modified Yinchen Decoction in Treatment of Eczema in 56 Cases. Public Medical Forum Magazine, 2007,11(3):223.

[8]Xin ZhangHao. Modified Yinchen Decoction in Treatment of Cholestatic Hepatitis in 58 Cases. Journal of Practical Traditional Chinese Medicine,2008,24(3):152.

[9]Yuan YuWen. Clinical Analysis of Yinchen Decoction in Treatment of Biliary Ascariasis in 78 Cases. Hunan Journal of Traditional Chinese Medicine,1992(3):21-22.