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[English Name] Willowleaf Hygrophila Herb
[Chinese Name] 水蓑衣  
[Pinying Name] Shuisuoyi  
[Latin Name] Hygrophilae Salicifoliae Herba  
[Genera] Acanthaceae
[Efficacy] Antipyretic drug
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology] It grows in stream side and ditch side or dank grass.  
[Chemical composition]  
[Pharmacological activities]

1Diuresis: Hygrophila salicifolia containthe sylvite, so it had the diuresis effects[1].

2Protection liver: This had acute hepatic injury induced by carbon tetrachloride(CCl4) 10 mL/kg injected intraperitoneally. The extraction from hygrophiiasalicifoiia can protect the liver from damage induced by CCI4 in adose-dependent manner[2].

3Anti-Hepatocarcinoma: Subcu-taneouslyinjected with human HCC cells. The extraction from hygrophila salicifoliacan significantly inhibit the growth of hepatocarcinoma cell xenografts in nudemice in a dose-dependent manner[3].

 
[Clinical trial]

Shuisuoyi (Hygrophila salicifolia)

1 Suppurative infection: The treatment group use 3%hydrogen peroxide solution2% Yau locksolution flushing repeatedly first, then disinfection the surface of a woundwith the iodophor stoste,final extra-apply the surface of wound with shuisuoyiseeds add 0.1% ethacridine lactate liquid,change the medicine every day untilcured.The control group disinfection the skin with 3% hydrogen peroxidesolution and iodophor stoste,then wet extra-apply the surface of wound with0.1% ethacridine lactate,change the medicine every day until cured.40 cases inthe 2 groups respectively. Results: Result: The treatment group has remarkedeffective than the control group on therapy pyogenic infection wound (includingulcerative necrosis tissue period bedsore) (P <0.05), can shorten the courseof treatment (P <0.01), relieve the pain and economic burden of patients[1].

2 large and deep bedsoreWish thesurface of wound with 3% hydrogen peroxide, 2% eusol repeatedly, wipe out theconfirmed necrotic tissue. Extra-apply the surface of wound with Shuisuoyiseeds (Hygrophila salicifolia sub) and 0.1% rivanol solution, 1-2 times a day,until cured. Result: 2-3 days later, granulation tissue growth on the surfaceof wound. at least  exchange medicine 7times, the most up to 68 times; The shortest treat time was 7 days , longest of65 days, an average of 25.8 days, the total effective rate was 100%[2] .

3 Lower limbs and scrotum ulcer: Extra-apply the wound withshuisuoyi seeds and Hygrophila Salicifolia with Gary Van Nor externalapplication wound, exchange medicine every day, 2 weeks a course. Treat lowerlimb ulcer 25 cases, scrotal ulcer 18 case. Result: 38 cases cured at the firstcourse, the remained 5 cases cured at the second course. The cure rate was100%. Medicine exchanges at least 3 times, 48 times at most, the average of 12.6times. The shortest treat time was 3 days, longest was 25 days, the average of10.2 days [3].

4 Extravasation of mannitol induced local swelling oftissues: Treatment group use Hygrophila Salicifolia add water and externalapplication the wound, 4h replace 1 time. The control group externalapplication the wound with the gauze which impregnated 50% magnesium sulfate,2h replace 1 time. Result: The treatment group swelling degrade time wassignificantly precede than the control group (P<0.05), curative effect isbetter than the control group [4].

5 Acute mastitis : Hygrophila Salicifolia add warm waterand external application the affected part, every 24-36h exchange a time. Treat50 cases. Result: All cured, 10 cases cured in 2 times, 3 times cure 25 cases,4 times cure 15 cases [5].

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]

1.       Hematemesis due to trauma

2.       overstrain, pain due to trauma

3.       Whooping cough

 
[Toxicological studies]  
[Pharmaceutical preparations]  
[References]

Pharmacology Actions:

[1] Chuan-long Yu, Tai-kang Huang, Zhi-zhun Ding et al., Chinese medicine Ci Hai (Volume I) .1st edition, Beijing: China Medical Science and Technology Press, 1993: 296.

[2] Da-ming Feng, Shuang Wang, Ya-ling Tang et al., Protective effect of extraction from Hygrophila sallclfolla on mice acute hepatic injury, World Chin J. Digestol, 2005, 13 (9): 1098.

[3] Da-ming Feng, Shuang Wang, Bi-hua Dong et al., Hygrophila extract on the nude mice liver tumor growth, World Chin J. Digestol, 2005,13(07):864
Clinical experiment

[1] Zeng XiaoFang. Nantian Xianzi compress in treatment ofpyogenic infection curative effect observation, Chinese Journal of Pathology,2007, 7(16):3714

[2] Zeng XiaoFang.Application of combination of traditional Chinese and Western medicine intreating large area deep bedsore, Modern nursing, 2003, 9(5):373

[3]Li JiaMei. Nantian Xianzi compress in treatment of lowerlimb Scrotal ulcer clinical observation of 43 cases. Chinese Journal of Medicine .1998, 33(5):58.

[4] Luo QunYing. Nantian Xianzi wet compress with magnesiumsulfate wet dressing treating mannitol extravasation effect comparison. Modernmedicine & Health , 2006,22(4): 569

[5] Zhang YouLi. Nantian Xianzi compress in treatment of 50cases of acute mastitis. Chinese Journal of integrated traditional and Westernmedicine , 1992,(7):423