The root tuber contains glycoside: ophiopogonin B、D (the aglycone is ruscogenin);  (23S,24S,25S)-23,24-dihydroxyruscogenin-1-O-[α-L-rhamnopyranosyl(1→2)][β-D-xylopyranosyl(1→3)]-α-L-arabinopyranoside-24-O-β-D-fucopyranoside、 (23S,24S,25S)-23,24-dihydroxyruscogenin-1-O-[α-L-2,3,4-tri-O-acetylrhamnopyranosyl(1→2)][β-D-xylopyranosyl(1→3)]-α-L-arabinopyranoside-24-O-β-D-fucopyranoside、(23S,24S,25S)-23,24-dihydroxyruscogenin-1-O-[α-L-4-O-acetylrhamnopyranosyl(1→2)][β-D-xylopyranosyl(1→3)]-α-L-arabinopyranoside-24-O-β-D-fucopyranoside[ the aglycone is (23S,24S,25S)-23,24-dihydroxyruscogenin ]; Ophiopogonin D′、diosgenin-3-O-[α-L-rhamnopyranosyl(1→2)]-(3-O-acetyl)-β-D-xylopyranosyl(1→3)-β-D-glucopyranoside 、diosgenin-3-O-[(2-O-acetyl）-α-L-rhamnopyranosyl(1→2）]-β-D-xylopyranosyl(1→3）-β-D-glucopyranoside (the aglycone is diosgenin) ; ophiogenin-3-O-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside(the aglycone is ophiogenin) ; borneol-2-O-β-D-glucopyranoside、borneol-2-O-β-D-apiofuranosyl(1→6)-β-D-glucopyranoside、 borneol-2-O-α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside(the aglycone is borneol) ; It also contains homoisoflavonoid: methylophiopogonanone A、B, 6-aldehydo-7-O-methylisoophiopogonanone A、B, 6-aldehydoisoophiopogonone A、B, ophiopogone A, desmethylisoophiopogonone B, 5,7,2′-trihydroxy-6-methyl-3-(3′,4′-methylenedioxybenzyl)chromone, 5-hydroxy-7,8-dimethoxy-6-methyl-3-(3′,4′-dihydroxybenzyl)chromanone; ruscogenin-1-O-sulfate, ophiogenin, calciumbornyl sulfate, glycerol, N-[β-hydroxy-β-(4-hydroxy)phenyl]ethyl-4-hydroxycinnamide, β-sitosterol, stigmasterol, β-sitosterol-3-O-β-D-glucopyranoside.

It contains essential oils: longifolene, α-patchoulene, β-patchoulene, cyperene, guaiol, α-humulene, camphor, linalool, terpinen-4-ol, jasmololone; elements: K, Na, Ca, Mg, Fe, Cu, Co, Mn, Cr, Pb, Ni, Ba, Zn, etc^[1].

1 Effect on the cardiovascular system: (1) the impact on cardiac function: intravenous injection of 10g(crude drug)/kg ophiopogon injection fluid, indexes of  anesthetized dogs such as the ratio of left ventricular pressure rise rate and total pressure(Vpm), aortic root flow, cardiac output(CO), work of left ventricle can be improved. And it also can prevent cardiac ejection dysfunction caused by the anterior descending branch of left coronary artery ligation and have the function of enhancing cardiac hemodynamic; Given patients of coronary artery disease with angina and cardiac dysfunction 40g(crude drug)/kg intravenous injection 7 times, not only stroke index(CI), stroke work index and cardiac index(CI) significantly improved, but also the ratio of pre-ejection and left ventricular ejection time. This change is not only in the short period after injection, but also become more apparent with treatment days increasing [1]. intravenous injection of anesthetized cats with 1.75g/kg water-soluble extract of Hubei ophiopogon japonicus  can mild slow down the heart rate, decreased systemic vascular resistance, increase ventricular pressure change rate, shorten the time between starts to contract and ejection of left ventricle, significant increase in CO, CI, SI, and left ventricular work index, and has the function of positive inotropic and improve cardiac pump [2]. Ophiopogon japonicus Renshi solution can improve myocardial contractility in low concentrations,  but inhibit myocardial contractility in high concentrations to induce the heartbeat is extremely weak, but not arrest. Contractility can be restored when switching to ophiopogon japonicus Renshi solution, indicates that it has little toxicity to the myocardium [3]. Ophiopogon japonicus saponin markedly enhanced myocardial contractility in isolated toad heart and increase cardiac output. Ophiopogon japonicus total saponins and total amino acids can enhance myocardial contractility and coronary flow in small doses while in high doses can inhibite cardiac muscle and reduce coronary blood flow, but neither of them have effect on heart rate [4]. Continuous intravenous injection 6g(crude drug)/kg ophiopogon japonicus injection for 3days can cause hemodynamic changes in rats with heart failure after myocardial infarction and adjust left ventricular function quickly [5]. (2) Myocardial protection: Mice received continuous intraperitoneal injection of 50g(crude drug)/kg ophiopogon japonicus injection for 3 days can significantly reduce the hypoxic damage of myocardial cells after long time swim. Ligaturing rabbit coronary anterior descending, when the experimental myocardial infarction occurs, continuous intravenous injection of 5g(crude drug)/kg ophiopogon japonicus injection for 5 days, infarction region and necrosis area shrinked [6]. Intraperitoneal injection of 5mg/kg ophiopogon japonicus total amino acid can do good to pituitrin induced rat electrocardiogram and protect from acute ischemia variation. Intraperitoneal injection of Tal10mg/kg can confront ST segment elevation and isoproterenol-induced myocardial injury in rats, and significantly inhibit the release of myocardial tissue creatine phosphokinase (CPK), reduce the serum CPK level, keep the superoxide dismutase activity of myocardial tissue and reduce malonaldehyde production. For myocardial infarction rat of coronary ligation, intraperitoneal injection of Tal15mg/kg can significantly inhibit the elevated serum CPK and lactate dehydrogenase, lower serum free fatty acid levels and reduce myocardial infarction region. The results show that Tal has a significant protective effect on experimental myocardial ischemia [7]. Different doses of ophiopogon japonicus polysaccharides(MDG-1) can significantly increase coronary blood flow of the isolated guinea pig heart ischemia and reperfusion, rapidly recover cardiac contraction amplitude and obviously inhibit ischemia-reperfusion-induced heart rate speed up. Administered intragastrically MDG-140mg/kg to rats can markedly suppress isoproterenol induced myocardial ischemia rat plasma lactate dehydrogenase activity increased but have no significant impact on the ECG ST-segment displacement. The results showed that MDG-1 plays the role of protecting guinea pig isolated heart from ischemia and reperfusion injury,  intragastric administration of MDG-1 has the protection of isoproterenol-induced rat myocardial ischemia injury [8]. (3) anti-arrhythmic effects: intravenous injection of 10mg/kg ophiopogon japonicus total saponins can effectively prevent chloroform - adrenergic, barium chloride and aconitine induced rat or rabbit arrhythmia, and reduce the incidence of ventricular arrhythmias 24 hours later of the ligation of the canine coronary. 15mg/kg ophiopogon japonicus total saponins can significantly reduce the maximal rate of monophasic action potential(Vmax) of rabbit, shorten the time of action potential complex pole 10%(APD10) and action potential complex pole 50%(APD50). 50mg/kg ophiopogon japonicus total saponins can lower transmembrane action potential amplitude of guinea pig papillary muscle cell, significantly reduce Vmax, APD10 APD50, and at the same time, action potential duration increased obviously [9].

2 Influence of the immune function: intraperitoneal injection of 12.5g(crude drug)/kg ophiopogon japonicus or Hubei ophiopogon japonicus can significantly increase mice spleen weight, markedly increase mice carbon clearance ability and fight against cyclophosphamide caused mice white blood cell decline [10]. Intraperitoneal injection of MDG-110g/kg can markedly increase mice spleen weight, significantly increase mice carbon clearance ability, stimulate the production of serum hemolysin, resist cyclophosphamide and 60CO irradiation caused mice white blood cell decline, and enhance the rabbit erythrocyte agglutination [11]. Intragastric administration of 1600mg/kg and 400mg/kg ophiopogon japonicus polysaccharide plays a certain role in the recovery of 60Co-γ-ray and cyclophosphamide caused mice immune organ damage, and it can significantly enhance thymus and spleen weight of the low immunization mice, elevate white blood cell count of cyclophosphamide injected mice [12].

3. Hpyerglycemic: intragastric administration of 200mg/kg ophiopogon japonicus water extracts to normal rabbits, the glucose decreased more than 18% 6 hours later. Continuous intragastric administration of 500mg/kg ophiopogon japonicus water extracts to experimental diabetic rabbits fro 4 days, the glucose downgraded, islet β-cell recovery and liver glycogen increased [13]. intragastric administration of 100mg/kg ophiopogon japonicus polysaccharide to normal mice can significantly lower blood sugar and 11 hours later, blood glucose concentration decreased by 54%. Intragastric administration of 200mg/kg ophiopogon japonicus polysaccharide to alloxan-induced diabetic mice can significantly lower blood sugar and after 4 to 11 hours, the hypoglycemic effect of the most significant. Of note, the effect of ophiopogon japonicus polysaccharide does not enhance with the dose increase [14]. 14 days in a row, intragastric administration of 200mg/kg ophiopogon japonicus polysaccharide can reduce blood sugar of gestational diabetic rats [15]. Intragastric administration of 250mg/kg ophiopogon japonicus can perfectly treat gestational diabetes and change the insulin resistance state, and its mechanism relates to the mRNA expression changes of protein hormone secreted by tumor necrosis factor-α and fat cells [16]. Intragastric administration of 200mg/kg and 400mg/kg ophiopogon japonicus total saponins can suppress alloxan, epinephrine and glucose-induced hyperglycemia in mice [17].

4. Antioxidant and anti-aging: ophiopogon japonicus extract has a strong scavenging effect to xanthine-oxidases fenton reaction and the reactive oxygen free radicals generated by cancer-promoting agent fourteen acyl phorbol acetate stimulates human polymorphonuclear leukocytes respiratory burst at the concentration of 1%[18]. Ophiopogon japonicus root in feed fed mice can reduce body hydroxyproline. The inhibition rate of male mouse brain monoamine oxidase (MAO-B) is 38.6% and liver superoxide dismutase (SOD) activity increased by 45.5%. Ophiopogon japonicus root prolong life of fruit flies, suggesting that there are anti-aging trend [19]. The inhibition of 1.25mg/mL ophiopogon japonicus water-soluble polysaccharide to hydroxyl radicals in vitro is 40.99% [23]. 1×102μmol/L ophiopogon japonicus saponins act on hydrogen peroxide induced chondrocyte can resist H2O2 reduced chondrocyte survival rate and elevate SOD content in the culture medium [20]. Intraperitoneal injection of 1g(crude drug)/kg ophiopogon japonicus injection can improve learning and memory function in rats and a variety of tissues of SOD, glutathione peroxidase levels increased [21].

5. Gastrointestinal motor function: perfusion of 30g/kg and 60g/kg ophiopogon japonicus decoction liquid both can significantly inhibit gastrointestinal propulsive motility of normal mice, and with the increase of drug dose, this inhibition was enhanced. And it also showed antagonism effect to neostigmine nromide induced mouse gastrointestinal propulsive movement hyperthyroidism and acetylcholine or barium chloride caused tonic contraction of isolated small intestinal smooth muscle [22].

6. Sedative and hypnotic: intragastric administration of 20g(crude drug)/kg ophiopogon japonicus can significantly inhibit the spontaneous activity, markedly prolong sleep time of mice pentobarbital co-threshold dose, and has a significant sedative effect [23 ].

7. Hypoxia tolerance: intraperitoneal injection of 50g(crude drug)/kg ophiopogon japonicus injection can significantly improve hypoxia tolerance of subcutaneous injection of isoproterenol mice under conditions of hypobaric hypoxia [24]. Intraperitoneal injection of 25g(crude drug)/kg ophiopogon japonicus injection can markedly improve hypoxia tolerance in mice at atmospheric pressure and decompression [25]. Intraperitoneal injection of 20mg/kg ophiopogon japonicus polysaccharide significantly prolong the survival time of hypoxic mice [26].

8. Antibacterial: ophiopogon japonicus powder has inhibition of white aureus, bacillus subtilis, escherichia coli and salmonella typhi in vitro [27]. Ruscogenin also has an antibacterial effect [28].

9. Anti-tumor effect and anti-radiation: intraperitoneal injection of 10-40mg/kg liriope muscari saponin C has antitumor activity on Ehrlich ascites carcinoma, intraperitoneal injection or subcutaneous injection of 20mg/kg can suppress the activity of  sarcoma s180, and only 10mg/kg dose can confront the effects of 60Co-γ-ray irradiation-induced leukopenia [29].

10. Anti-allergy: ophiopogon japonicus polysaccharide has a more significant anti-mouse ear dissimilar passive cutaneous anaphylaxis, and it can be the antagonism of bronchial smooth muscle contraction of acetylcholine and histamine mixture stimulated the normal guinea pig or ovalbumin induced sensitized guinea pig and suppress sensitized guinea pig asthma and mouse mast cell degranulation and histamine release, so it has significant effect of anti-type I allergy [30].

1. Sicca syndrome: The treatment of sicca syndrome withMaidongtang in 20 cases, an agent per day, take it in morning and eveningpoints Results showed that 8 cases  of treatmentgroup were markedly improved, 8 cases were effective,the total effective rate was80%^[1].

2. Chronic pharyngitis:(1) Maidongtang,an agent per 2 days,10 days as one course of treatment,43cases were treated,17 cases were cured, 23cases were improved,3 cases wereinvalid, the total effective rate was 93%^[2] .(2)45 cases were treatd,26 cases werecured (57.78%),16cases were improved (35.55%),3 cases were invalid, (6.67%), the total effective rate was 93.33%^[3].

3. Intractablehiccups: As tea drink, 10 days as one courses of  treatment, that were treated for 2 or 3courses. 15 cases were treated, it was a course obviously improved and stopdrug hiccups in 5 cases, For three courses symptoms was disappeared in 10 cases^[4]. 

1.Niaoduling Enema: rhubarb, glabrous greenbrier rhizome,forsythia fruit, capejasmine fruit, cogongrass Rhizome, cinnamom twig,honeysuckle flower, sanguisorba root, natural indigo, phellodendron bark,dragon’s bone(calcining), oyster shell(calcining), sophora flower, uncaria stemwith hooks, puncturevine caltrop  fruit,red sage root, safflower, dried fresh ginseng, ophiopogon root, wolfberryfruit.

2.Angong Jiangya Pill: cow bezoare, pulvis cornus bubaliconcentratus, gastrodia tuber, coptis root, capejasmine fruit, curcuma root,borneol, pearl shell, milkvetch root, dangshen, ophiopogon root, white peonyroot, schisandra fruit(stir-frying), chuanxiong rhizome.

3.Qingxuan Zhitan Pill: gastrodia tuber, batryticatedsilkworm, scorpion, earthworm, pearl, cassia seed, pulvis cornus bubaliconcentratus, cow bezoare, coptis root, scutellaria root, red sage root,chuanxiong rhizome, red peony root, achyranthes root, myrrh(stir-frying withvinegar), draconis resin, clematis root, giant typhonium tuber(stir-frying withalum water), long-nosed pit viper(stir-frying with wine), processed pinelliatuber, benzoin, borneol, ginseng(removing LU), milkvetch root, whiteatractylodes rhizome(stir-frying), poria, ophiopogon root, scrophularia root,dried rehmannia root, fortune’s drynaria rhizome, loranthus mulberry mistletoe,eagle wood, nutgrass flatsedge rhizome(stir-frying with vinegar), curcuma root,immature bitter orange(stir-frying), pueraria root, sophora flower, orientalwater plantain rhizom, hawthorn fruit.

4.Niuhuangqingxin Pill: cow bezoare, anteplope’s horn,pulvis cornus bubali concentratus, scutellaria root, Japanese ampelopsis root,dried black soybean sprout, bitter apricot kernel(stir-frying), platycodonroot, ledebouriella root, bupleurum root, musk, borneol, cinnabar, realgar,chuanxiong rhizome, cat-tail pollen(stir-frying), ginseng, white atractylodesrhizome(stir-frying), poria, chinese yam, liquorice, chinese date(stoned),chinese angelica root, white peony root, ass hide glue , ophiopogon root, driedginger, medicated leaven(stir-frying), chinese cassia bark.

5.Guogong Medicinal Liquor: notopterygium root, pubescentangelica root, ledebouriella root, acanthopanax bark, atractylodesrhizome(stir-frying), chuanxiong rhizome, dahurian angelica root, agastache,arisaema tuber(stir-frying with alum water), chaenomeles fruit, whiteatractylodes rhizome（stir-fryingwith bran）,areca seed, magnolia bark, orange fruit（stir-frying with bran）,tangerine peel, green tangerine orange peel(stir-frying with vinegar), linderaroot, finger citron, safflower, mutan bark, arnebia(or lithosperm) root, redcolouring rice used as a chinese medicine, chinese angelica root, white peonyroot, psoralea fruit(stir-frying with salt-water), wolfberry fruit, achyranthesroot, ophiopogon root, fragrant solomonseal rhizome, capejasmine fruit.

6.Baihegujin Pill(Oral Liquid): lily bulb, prepared rehmanniaroot, tendrilleaf fritillary bulb, scrophularia root, dried rehmannia root,chinese angelica root, white peony root, platycodon root, liquorice.

7.Yangyin Qingfei Cream(Syrup, Oral Liquid, Pill): driedrehmannia root, scrophularia root, ophiopogon root, white peony root, mutanbark, tendrilleaf fritillary bulb, Menthol, liquorice.

8.Erdong Cream: cochinchinese asparagus root, ophiopogonroot.

9.Juhongli Cream: pear, ophiopogon root, cochinchineseasparagus root, pummelo peel, bitter apricot kernel, loquat leaf, tendrilleaffritillary bulb, schisandra fruit.

10.Juhong Pill: pummelo peel, thunberbg fritillary bulb,tangerine peel, pinellia tuber(prepared), poria, liquorice, bitter apricotkernel, purple perilla leaf(stir-frying), platycodon root, aster root,coltsfoot flower, snakegourd peel, gypsum, dried rehmannia root, ophiopogonroot.

11.Baikejing Syrup: scutellaria root, tangerine peel,mulberry bark, snakegourd seed(stir-frying), alum processed pinellia, arisaematuber(stir-frying), ephedra(stir-frying with honey), bitter apricotkernel(stir-frying), purple perilla seed(stir-frying), platycodon root,peucedanum root, lepidium seed(stir-frying), phellodendron bark, stemonaroot(stir-frying with honey), ophiopogon root, liquorice.

12.Compound Baibuzhike Syrup(Granule): stemonaroot(stir-frying with honey), scutellaria root, bitter apricot kernel, mulberrybark, orange fruit(stir-frying), arisaema tuber(prepared), platycodon root,tangerine peel, ophiopogon root, anemarrhena rhizome, liquorice.

13.Zhikejuhong Pill(Capsule,Granule,Oral Liquid): pummelopeel, snakegourd peel, tangerine peel, processed pinellia tuber, poria, gypsum,anemarrhena rhizome, aster root(stir-frying), bitter apricot kernel(removingpeel and stir-frying), aster root, coltsfoot flower, platycodon root, driedrehmannia root, ophiopogon root, liquorice.

14.Zhike Huatan Granule(Pill): platycodon root, bitter apricotkernel, lepidium seed, coltsfoot flower(prepared), peucedanum root, tendrilleaffritillary bulb, snakegourd seed, aristolochia fruit(prepared), stemonaroot(prepared), gypsum, anemarrhena rhizome, scrophularia root, ophiopogonroot, cochinchinese asparagus root, purple perilla leaf, mulberry leaf, palebutterflybush flower, tangerine peel, pinellia tuber（stir-fryingwith ginger juice）,orange fruit(stir-frying), aucklandia root, poppy capsule, schisandrafruit(prepared), rhubarb(prepared), stir-fried liquorice.

15.Lingyangqingfei Granule(Pill): anteplope’s horn powder,scutellaria root, mulberry bark(stir-frying with honey), rhubarb(steaming),capejasmine fruit, mutan bark, isatis leaf, isatis root, honeysuckle flower,bitter apricot kernel(stir-frying), platycodon root, tangerine peel, thunberbgfritillary bulb, tinospora root, peppermint, loquat leaf(stir-frying withhoney), peucedanum root, dried rehmannia root, scrophularia root, dendrobium,cochinchinese asparagus root, ophiopogon root, trichosanthes root, liquorice.

16.Ermu’ansu Pill: anemarrhena rhizome, thunberbgfritillary bulb, coltsfoot flower, aster root, bitter apricot kernel,scrophularia root, ophiopogon root, lily bulb, poppy capsule.

17.Qiuzaoganmao Granule: mulberry leaf, chrysanthemumflower, bitter apricot kernel(stir-frying), fritillaria, platycodon root,peucedanum root, coastal glehnia root, ophiopogon root, subprostrate sophoraroot, lophatherum herb, liquorice.

18.Chuanbeixueli Cream: pear ointment, tendrilleaffritillary bulb, ophiopogon root, lily bulb, coltsfoot flower.

19.Liqidingchuan Pill: purple perilla leaf andseed(stir-frying), purple perilla leaf and stem, purple perilla leaf, tangerinepeel, processed pinellia tuber, mustard seed(stir-frying), radishseed(stir-frying), bitter apricot kernel(stir-frying), tendrilleaf fritillarybulb, mulberry bark(stir-frying with honey), coltsfoot flower, aster root,milkvetch root(stir-frying), poria, white atractylodes rhizome（stir-fryingwith bran）,lily bulb, anemarrhena rhizome, ophiopogon root, cochinchinese asparagus root,dried rehmannia root, chinese angelica root, fleece flower root(stir-fryingwith soybean wine), ass hide glue （stir-frying with tokay gecko powder）.

20.Ruyidingchuan Pill: ephedra, bitter apricot kernel, gypsum,stir-fried liquorice, stemona root, immature bitter orange, aster root,earthworm, ginkgo seed, polygala root, lepidium seed, datura flower, toadvenom(prepared), milkvetch root, dangshen, prepared rehmannia root,cochinchinese asparagus root, ophiopogon root, wolfberry fruit, tokay gecko,schisandra fruit(steaming with wine).

21.Bujin Tablet: deerhorn glue, dried human placenta,tortoise carapace and plastronglue, tokay gecko(removing feet and head),oviductus rannae, oil of gallus gallus domesticus brisson, black-tailsnake(removing  head and stir-frying),red ginseng, chinese angelica root, peach kernel, siberian solomonsealrhizome(steaming), ophiopogon root, poria, tangerine peel, thunberbg fritillarybulb, stemona root(stir-frying with honey), platycodon root, hyacinth bletilla.

22.Gubenkechuan Tablet: dangshen, hyacinth bletilla（stir-fryingwith bran）,poria, psoralea fruit(stir-frying with salt water), ophiopogon root, schisandrafruit(processing with vinegar), stir-fried liquorice.

23.Gajiedingchuan Capsule(Pill): tokay gecko, lily bulb, purpleperilla leaf(stir-frying), bitter apricot kernel(stir-frying), aster root,snakegourd seed, ephedra, scutellaria root, coptis root, gypsum,gypsum(calcining), ophiopogon root, liquorice.

24. Moluo Pill: lily bulb, poria, whiteatractylodes rhizome（stir-fryingwith bran）,corydalis tuber(stir-frying with vinegar), lindera root, membrane of chickengizzard(stir-frying), chuanxiong rhizome, cat-tail pollen, chinese angelicaroot, white peony root, ophiopogon root, dendrobium, scrophularia root,notoginseng, sanguisorba root, grassleaved sweetflag rhizome, orientalwormwood, oriental water plantain rhizom.

25.Piantanfuyuan Pill: milkvetch root, ginseng, chineseangelica root, prepared rehmannia root, white atractylodesrhizome(stir-frying), poria, oriental water plantain rhizom, round cardamonseed, chuanxiong rhizome, red peony root, red sage root, notoginseng, achyranthesroot, gastrodia tuber, batryticated silkworm(stir-frying), scorpion, uncariastem with hooks, giant typhonium tuber(stir-frying with alum water), earthworm,processed pinellia tuber, large-leaf gentian root, clematis root, ledebouriellaroot, eucommia bark(carbonizing), psoralea fruit(stir-frying with salt-water),fortune’s drynaria rhizome, nutgrass flatsedge rhizome(stir-frying withvinegar), eagle wood, orange fruit(stir-frying), chinese cassia bark, cinnamomtwig, borneol, benzoin, ophiopogon root, liquorice.

26.Xintong Oral Liquid: milkvetch root, dangshen,pueraria root, ophiopogon root, chinese angelica root, fleece flower root,epimedium, sargassum, japanese sea tangle, oyster shell, Chinese honeylocustspine, immature bitter orange.

27.Shengmai Injection: red ginseng, ophiopogon root, schisandrafruit.

28.Kang’erxin Capsule: ginseng, ophiopogon root, notoginseng,red sage root, hawthorn fruit, wolfberry fruit, fleece flower root.

29.Xinrong Oral Liquid: milkvetch root, dried rehmanniaroot, red peony root, ophiopogon root, schisandra fruit, cinnamom twig.

30.Yinxin Capsule: ginseng, ophiopogon root, schisandrafruit, chinese angelica root, anemarrhena rhizome, grassleaved sweetflagrhizome.

31. YixinFumai Granule: dried fresh ginseng, milkvetch root, redsage root, ophiopogon root, schisandra fruit, chuanxiong rhizome.

32.Yixinshu Capsule: ginseng, milkvetch root, red sage root,ophiopogon root, schisandra fruit, chuanxiong rhizome, hawthorn fruit.

33.Qidongyixin Oral Liquid: milkvetch root, ophiopogon root,dried fresh ginseng, poria, dried rehmannia root, tortoise carapace andplastron(scalding), red sage root, curcuma root, cinnamom twig,fluorite(calcining), epimedium, honeysuckle flower, orange fruit(stir-frying).

34.Shenmai Injection: red ginseng, ophiopogon root.

35.Guanxinshengmai Oral Liquid: ginseng, ophiopogon root,schisandra fruit(stir-frying with vinegar), red sage root, curcuma root, redpeony root, notoginseng.

36.Zixinyin Oral Liquid(Granule, Capsule): ophiopogonroot, coastal glehnia root, red peony root, notoginseng.

37.Shenhailong Capsule: pipefish, epimedium, sea horse,pilose antler, goat or sheep testicle（scalding with sand）,common cnidium fruit, desertliving cistanche, prepared common monkshoodbranched root, dried ginger, chinese angelica root, cochinchinese asparagusroot, prepared rehmannia root, wolfberry fruit, ophiopogon root, ginseng,milkvetch root, chinese date, chinese yam, poria, schisandra fruit, achyranthesroot, peach kernel, leech, mutan bark, amomum fruit, stir-fried liquorice.

38.Quanlv Pill: venison, psoralea fruit(stir-frying withsalt water), songaria cynomorium herb(stir-frying with wine), eucommiabark(stir-frying with salt water), dodder seed, desertliving cistanche,papermulberry fruit, faenum graecum(stir-frying with wine), morinda root,dipsacus root(stir-frying with salt water), pricklyash peel, common fennelfruit(stir-frying with wine), schisandra fruit(steaming), palmleaf raspberryfruit, gordon euryale seed, dangshen, milkvetch root(stir-frying), poria, whiteatractylodes rhizome(stir-frying), chinese yam, stir-fried liquorice, preparedrehmannia root, chinese angelica root(stir-frying with wine), cochinchineseasparagus root, ophiopogon root, wolfberry fruit(stir-frying with salt water),dried rehmannia root, halite, tangerine peel, eagle wood, achyranthes root,chuanxiong rhizome(stir-frying with wine).

39.Yubiao Pill: air bladder of large yellowcroaker(stir-frying)（talcscalding）,achyranthes root, dogwood fruit(stir-frying with wine), palmleaf raspberryfruit, morinda root（stir-fryingwith liquorice）,eucommia bark(carbonizing), dodder seed, desertliving cistanche(stir-fryingwith wine), flatstem milkvetch seed, degelatined deer-horn, deerhorn glue,lotus stamen, dendrobium, cochinchinese asparagus root, ophiopogon root, driedrehmannia root, prepared rehmannia root, chinese angelica root, wolfberryfruit, schisandra fruit(stir-frying with vinegar), chinese yam, whiteatractylodes rhizome（stir-fryingwith bran）,pricklyash peel(stoned), aucklandia root, red halloysite（calciningcalcining and quenching with vinegar）, poria, oriental water plantain rhizom,plantain seed(stir-frying with salt-water), wild or spring jujubaseed(stir-frying), arborvitae seed, polygala root（stir-frying with liquorice）,grassleaved sweetflag rhizome, wolfberry bark.

40.Hechedazao Pill: prepared rehmannia root, tortoisecarapace and plastron(stir-frying with vinegar), dried human placenta,cochinchinese asparagus root, ophiopogon root, eucommia bark(stir-frying withsalt water), achyranthes root(stir-frying with salt water), phellodendronbark(stir-frying with salt water).

41.Maiweidihuang Oral Liquid: prepared rehmannia root, dogwoodfruit(prepared), chinese yam, ophiopogon root, mutan bark, poria, orientalwater plantain rhizom, schisandra fruit.

42.Manganyangyin Capsule: dried rehmannia root, wolfberryfruit, coastal glehnia root, chinese angelica root, dangshen, ophiopogon root,schisandra fruit, sichuan chinaberry, ginseng, cinnamom twig.

43.Yinxu Weitong Granule(tablet): coastal glehnia root, ophiopogonroot, dendrobium, fragrant solomonseal rhizome, sichuan chinaberry, white peonyroot, stir-fried liquorice.

44.Ganshen extract: wolfberry fruit, dangshen, ass hide glue, ophiopogon root, milkvetch root.

45.Zaizaoshengxue Pill: dodder seed(processing with wine),glossy privet fruit, eclipta, wolfberry fruit, siberian solomonsealrhizome(processing with wine), psoralea fruit(processing with salt water),pilose antler(removing hair), epimedium, milkvetch root, red ginseng, dangshen,white atractylodes rhizome(stir-frying), chinese angelica root, preparedrehmannia root, white peony root, prepared fleece flower root, ass hide glue ,suberect spatholobus stem, ophiopogon root, hairy vein agrimony, motherwort.

46.Yiqi Yangxue Oral Liquid: ginseng, milkvetch root, chineseangelica root, prepared fleece flower root, dangshen, white atractylodesrhizome(stir-frying), pilose antler, dried rehmannia root, ophiopogon root,schisandra fruit, epimedium, wolfberry bark, tangerine peel.

47.Xiaopiling Granule: ginseng, chinese angelica root,milkvetch root, poria, longan aril, ass hide glue , ophiopogon root, schisandrafruit, glossy ganoderma, suberect spatholobus stem, red sage root, wild orspring jujuba seed, chinese cassia bark, hawthorn fruit.

48.Yiqi Yangyuan Granule: dangshen, prepared rehmanniaroot, milkvetch root(stir-frying), white atractylodes rhizome（stir-fryingwith bran）,chinese angelica root, white peony root, ophiopogon root, dried human placenta,tangerine peel, polygala root（stir-frying with liquorice）,chinese cassia bark.

49.Shuyu Pill: chinese yam, ginseng, dried rehmanniaroot, white atractylodes rhizome（stir-frying with bran）,poria, liquorice, chinese date(stoned), chinese angelica root, white peonyroot, ass hide glue , ophiopogon root, chuanxiong rhizome, medicated leaven（stir-fryingwith bran）,dried ginger, bitter apricot kernel(removing peel and stir-frying), platycodonroot, cinnamom twig, bupleurum root, ledebouriella root, Japanese ampelopsisroot, dried black soybean sprout.

50.Shenrong’ajiao: donkey skin, chinese angelica root,chuanxiong rhizome, prepared rehmannia root, white peony root, ginseng,dangshen, white atractylodes rhizome, poria, liquorice, pilose antler, chinesecassia bark, fragrant solomonseal rhizome, ophiopogon root, safflower, mutanbark, dried rehmannia root, nutgrass flatsedge rhizome, aucklandia root, amomumfruit, tangerine peel, dahurian angelica root, alum processed pinellia.

51.Renshenguben Pill: ginseng, prepared rehmannia root, driedrehmannia root, dogwood fruit(stir-frying with wine), chinese yam, ophiopogonroot, cochinchinese asparagus root, oriental water plantain rhizom, mutan bark,poria.

52.Huangqishengmai Oral Liquid: milkvetch root, dangshen, ophiopogonroot, schisandra fruit.

53.Shengmaiyin Capsule: red ginseng, ophiopogon root,schisandra fruit.

54.Shenqijiangtang Capsule(Granule, Tablet): ginsengstemand leaf saponin, milkvetch root, chinese yam, ophiopogon root, schisandrafruit, wolfberry fruit, palmleaf raspberry fruit, dried rehmannia root,trichosanthes root, poria, oriental water plantain rhizom.

55.Tangniaoling Tablet: trichosanthes root, dried rehmanniaroot, pueraria root, ophiopogon root, schisandra fruit, pumpkin powder,polished glutinous rice(stir-frying), liquorice.

56.Shiweiyuquan Capsule: trichosanthes root, puerariaroot, dried rehmannia root, ophiopogon root, schisandra fruit, ginseng,milkvetch root, poria, black plum, liquorice.

57.Xiaokeling Tablet: dried rehmannia root, milkvetch root, wolfberryfruit, trichosanthes root, ophiopogon root, red ginseng, poria, gypsum, coptisroot, schisandra fruit, mutan bark.

58.Xinnaoshu Oral Liquid: ginseng, ophiopogon root,dangshen, milkvetch root, schisandra fruit.

59.Yangyin Shengxue Mixture: dried rehmannia root, milkvetchroot, chinese angelica root, ophiopogon root, dendrobium, scrophularia root,chuanxiong rhizome.

60.Yifeiqinghua Cream: milkvetch root, dangshen, coastalglehnia root, ophiopogon root, tendrilleaf fritillary bulb, bitter apricotkernel, aster root, platycodon root, patrinia, bistort rhizome, hairy veinagrimony, hedyotis, liquorice.

61.Quanfukang Oral Liquid: milkvetch root, coastal glehniaroot, cochinchinese asparagus root, ophiopogon root, glossy privetfruit(processing with wine), dogwood fruit, epimedium, faenumgraecum(stir-frying with salt water), gynostemma pentaphylla, doederlein’sspikemoss herb, all-grass of Chinese sage, paris root.

62.Qinggongchangchun Capsule: ginseng, prepared rehmanniaroot, poria, chinese yam, dodder seed(prepared), desertliving cistanche,achyranthes root, eucommia bark, palmleaf raspberry fruit, pricklyash peel,wolfberry fruit, dried rehmannia root, dogwood fruit(prepared), chineseangelica root, white peony root, cochinchinese asparagus root, ophiopogon root,schisandra fruit, arborvitae seed, grassleaved sweetflag rhizome, polygalaroot, oriental water plantain rhizom, aucklandia root, wolfberry bark.

63.Bushen Yinao Tablet: pilose antler(removing hair), redginseng, prepared rehmannia root, chinese angelica root, poria, chineseyam(stir-frying), wolfberry fruit, psoralea fruit, ophiopogon root, wild orspring jujuba seed(stir-frying), polygala root(stir-frying with honey),achyranthes root, scrophularia root, schisandra fruit, chuanxiong rhizome,cinnabar.

64.Shenrongweisheng Pill: pilose antler, cornu cervi,desertliving cistanche(processing with wine), pig kidneys, deer’s tail,prepared rehmannia root, chinese angelica root, white peony root, preparedfleece flower root, longan aril, wolfberry fruit, dried human placenta,ginseng, dangshen, milkvetch root, white atractylodes rhizome（stir-fryingwith bran）,songaria cynomorium herb, psoralea fruit(processing with salt water),achyranthes root, loranthus mulberry mistletoe, dipsacus root, cibot rhizome（scaldingwith sand）,dried rehmannia root, ophiopogon root, sal praeparatus, pig’s spinal cord,poria, atractylodes rhizome, amomum fruit, chaenomeles fruit, wild or springjujuba seed(stir-frying), polygala root(prepared), amber, tangerine peel,nutgrass flatsedge rhizome(processing with vinegar), aucklandia root, eaglewood, scutellaria root, alum processed pinellia, chuanxiong rhizome, safflower,frankincense(processing with vinegar), myrrh(processing with vinegar), dogwoodfruit(processing with wine), dragon’s bone, oyster shell, lotus seed,nutmeg(roasting), chinese date, liquorice.

65.Sanbao Capsule: pilose antler, desertliving cistanche,dodder seed(stir-frying), eucommia bark, dogwood fruit, fleece flower root,tortoise carapace and plastron(processing with vinegar), ophiopogon root,scrophularia root, prepared rehmannia root, chinese angelica root, ginseng,glossy ganoderma, chinese yam, schisandra fruit, mutan bark, red peony root,red sage root, oriental water plantain rhizom, chrysanthemum flower, amomumfruit(stir-frying).

66.cow bezoare清宫丸：composition:cowbezoare, musk, pulvis cornus bubali concentratus, honeysuckle flower, forsythiafruit, scutellaria root, capejasmine fruit, rhubarb, cinnabar, dried rehmanniaroot, ophiopogon root, scrophularia root, trichosanthes root, realgar, borneol,lotus plumule, curcuma root, liquorice.

67.YangyinZhenjing Tablet: chinese angelica root, ophiopogon root,schisandra fruit, tuber fleeceflower stem, dried rehmannia root, scrophulariaroot, arborvitae seed, dangshen, poria, pearl shell, cinnabar, red sage root,polygala root, platycodon root.

68.Yangxin Dingji Cream(Oral Liquid): driedrehmannia root, red ginseng, ophiopogon root, ass hide glue , stir-friedliquorice, chinese date, black sesame, cinnamom twig, fresh ginger.

69.Anshen Jiannao Oral Liquid: ginseng, ophiopogon root,schisandra fruit(stir-frying with vinegar), wolfberry fruit, red sage root.

70.Jiannao Anshen Tablet: siberian solomonsealrhizome(steaming), pilose antler, deerhorn glue, degelatined deer-horn,epimedium, wolfberry fruit, prepared rehmannia root, schisandra fruit, poria,polygala root(prepared), wild or spring jujuba seed(stir-frying), ophiopogonroot, tortoise carapace and plastron, red ginseng, chinese date(stoned),xanthium.

71.Huoliyuan Oral Liquid: ginsengstem and leaf saponins,ophiopogon root, schisandra fruit, milkvetch root, prepared common monkshoodbranched root.

72.Yinao Capsule: ginseng, glossy ganoderma, tortoisecarapace and plastronglue, schisandra fruit, dangshen, poria, ophiopogon root,dragon’s bone, grassleaved sweetflag rhizome, polygala root.

73.Xiegan Anshen Pill: gentian root, capejasminefruit(stir-frying with ginger juice), scutellaria root, wild or spring jujubaseed(stir-frying), arborvitae seed, polygala root（stir-frying with liquorice）, driedrehmannia root, chinese angelica root, pearl shell, oyster shell, dragon’sbone, puncturevine caltrop fruit(deburring and stir-frying with salt-water), ophiopogon root,poria, plantain seed(stir-frying with salt-water), oriental water plantainrhizom(stir-frying with salt-water), liquorice.

74.Xiaozuo Pill: gentian root, isatis leaf, scrophulariaroot, wild chrysanthemum flower, scutellaria root, honeysuckle flower,dandelion herb, lophatherum herb, prunella spike, arnebia(or lithosperm) root,bamboo shavings, gypsum, dendrobium, ophiopogon root, cimicifuga rhizome,bupleurum root.

75.Tiaojing Pill: nutgrass flatsedge rhizome(processingwith vinegar), motherwort, chinese angelica root, chuanxiong rhizome, mutanbark, myrrh(prepared), corydalis tuber(processing with vinegar), argyileaf(carbonizing), common fennel fruit(stir-frying with salt water), evodiafruit(prepared), ass hide glue , prepared rehmannia root, white peonyroot(stir-frying with wine), dipsacus root, white atractylodesrhizome(stir-frying), pinellia tuber(prepared), tangerine peel, poria,ophiopogon root, scutellaria root(stir-frying with wine), liquorice.

76.Fukangning Tablet: white peony root, chinese angelica root,dangshen, nutgrass flatsedge rhizome, notoginseng, motherwort, ophiopogon root,argyi leaf(carbonizing).

77.Fubao Granule: dried rehmannia root, white peonyroot(stir-frying with wine), eucommia bark叶(stir-frying with salt water), dipsacusroot, biota tops(stir-frying), lotus receptacle(carbonizing), corydalistuber(processing with vinegar), sichuan chinaberry(stir-frying),sargentgloryvine stem, honeysuckle stem, ophiopogon root, liquorice.

78.Shengruling: milkvetch root(stir-frying), dangshen,chinese angelica root, dried rehmannia root, scrophularia root, ophiopogonroot, anemarrhena rhizome, pangolin scales（heated with sand calcining and quenchingwith vinegar）.

79.Gengnian’an Tablet: dried rehmannia root, prepared rehmanniaroot, prepared fleece flower root, scrophularia root, ophiopogon root, poria,oriental water plantain rhizom, mutan bark, pearl shell, magnetite, uncariastem with hooks, tuber fleeceflower stem, schisandra fruit, light wheat,curculigo rhizome.

80.Kunbao Pill: fleece flower root(stir-frying withsoybean wine), dried rehmannia root, wolfberry fruit, glossy privetfruit(stir-frying with wine), eclipta, tortoise carapace and plastron, palmleafraspberry fruit, dodder seed, fourleaf ladybell root, ophiopogon root,dendrobium, chinese angelica root, white peony root, suberect spatholobus stem,red peony root, wolfberry bark, swallowwort root, anemarrhena rhizome,scutellaria root, mulberry leaf, chrysanthemum flower, pearl shell, wild orspring jujuba seed(stir-frying).

81.Xiao’eryanbian Granule: honeysuckle flower, belamcandarhizome, tinospora root, platycodon root, scrophularia root, ophiopogon root,cow bezoare, borneol.

82. Xiao’erchangweikangGranule: all-grass of Japan clover, all-grass ofcanton sonerila, pipewort flower, bat’s droppings, cicada slough, red peonyroot, silkworm faeces, dangshen, fragrant solomonseal rhizome, ophiopogon root,millet sprout, aucklandia root, liquorice, berberine hydrochloride.

83.Jian’erxiaoshi Oral Liquid: milkvetch root, whiteatractylodes rhizome（stir-fryingwith bran）,tangerine peel, radish seed(stir-frying), hawthorn fruit(stir-frying),scutellaria root, ophiopogon root.

84.Jian’ersu Granule: dangshen, white atractylodesrhizome(stir-frying), coix seed, fourleaf ladybell root, ophiopogon root, whitepeony root, germinated rice-grain(stir-frying), chebula fructus.

85.Erbao Granule(Cream): heterophylly falsestarwort root,coastal glehnia root, ophiopogon root, white peony root(stir-frying), poria,hyacinth bean (stir-frying), chinese yam, hawthorn fruit(stir-frying),germinated barley(stir-frying), tangerine peel, pueraria root(roasting).

86.Erkangning Granule: milkvetch root, dangshen, whiteatractylodes rhizome, poria, coix seed, chinese yam, chinese date, ophiopogonroot, prepared fleece flower root, hawthorn fruit(stir-frying), germinatedbarley(stir-frying), mulberry twig.

87.Xiao’erzhisu Syrup: scrophularia root, ophiopogon root,purple perilla leaf oil, trichosanthes root, bile arisaema, bitter apricotkernel水,platycodon root, bamboo shavings, anemarrhena rhizome, tendrilleaf fritillarybulb, mulberry bark, snakegourd seed, purple perilla seed(stir-frying), arecaseed(stir-frying), liquorice.

88.Xiao’erfeirekechuan Granule: gypsum, anemarrhena rhizome,honeysuckle flower, forsythia fruit, scutellaria root, houttuynia, isatis root,ophiopogon root, ephedra, bitter apricot kernel, liquorice.

89.Xiao’erfeirekechuan Oral Liquid: gypsum, anemarrhena rhizome,honeysuckle flower, forsythia fruit, scutellaria root, houttuynia, isatis root,ophiopogon root, ephedra, bitter apricot kernel, liquorice.

90.Xiao’erbaibuzhike Syrup: stemona root(processing withhoney, mulberry bark, scutellaria root, anemarrhena rhizome, bitter apricotkernel, platycodon root, arisaema tuber(prepared), tangerine peel, orangefruit(stir-frying), ophiopogon root, liquorice.

91.Longmuzhuanggu Granule: dangshen, milkvetch root, whiteatractylodes rhizome(stir-frying), chinese yam, poria, chinese date, membraneof chicken gizzard(stir-frying), ophiopogon root, tortoise carapace andplastron(processing with vinegar), dragon’s bone(calcining), oystershell(calcining), schisandra fruit(processing with vinegar), liquorice, calciumlactate, calcium gluconate, calciferol.

92. Le’erkangCapsule: dangshen, milkvetch root, heterophyllyfalsestarwort root, poria, coix seed, chinese yam, chinese date, preparedfleece flower root, ophiopogon root, hawthorn fruit(stir-frying), germinatedbarley(stir-frying), tangerine peel, mulberry twig.

93.Jianpishengxue Granule: dangshen, milkvetch root, poria,white atractylodes rhizome(stir-frying), chinese yam, schisandrafruit(processing with vinegar), ophiopogon root, tortoise carapace andplastron(processing with vinegar), chinese date, membrane of chickengizzard(stir-frying), dragon’s bone, oyster shell(calcining), liquorice,ferrisulfas.

94.Mingmushangqing Tablet: chrysanthemum flower, forsythiafruit, scutellaria root, coptis root, Menthol, schizonepeta oil, cicada slough,puncturevine caltrop  fruit, capejasminefruit, rhubarb(steaming), gypsum, trichosanthes root, ophiopogon root,scrophularia root, red peony root, chinese angelica root, plantain seed, orangefruit, tangerine peel, platycodon root, liquorice.

95.Hupohuanjing Pill: prepared rehmannia root, driedrehmannia root, desertliving cistanche(stir-frying with wine), eucommiabark(carbonizing), wolfberry fruit, dodder seed, flatstem milkvetch seed,cochinchinese asparagus root, ophiopogon root, anemarrhena rhizome, dendrobium,coptis root, phellodendron bark, dangshen(removing LU), chinese yam, poria,chinese angelica root, chuanxiong rhizome, amber, pulvis cornus bubaliconcentratus, anteplope’s horn powder, seed of feather cockscomb, chrysanthemumflower, bitter apricot kernel(removing peel and stir-frying), orange fruit（removingcorestir-frying with bran）, liquorice(stir-frying with honey).

96. ShihuyeguangGranule: dendrobium, cochinchinese asparagusroot, ophiopogon root, dried rehmannia root, prepared rehmannia root, wolfberryfruit, desertliving cistanche, dodder seed, schisandra fruit, 你想,ginseng, chinese yam, poria, liquorice, pulvis cornus bubali concentratus,anteplope’s horn, coptis root, cassia seed, seed of feather cockscomb,chrysanthemum flower, puncturevine caltrop fruit(stir-frying with salt water), chuanxiong rhizome, ledebouriellaroot, bitter apricot kernel, orange fruit(stir-frying).

97.Liyan Jiedu Granule: isatis root, isatis leaf, honeysuckleflower, forsythia fruit, peppermint, arctium fruit(stir-frying), trichosanthesroot, tendrilleaf fritillary bulb, rhubarb, scutellaria root, dried rehmanniaroot, scrophularia root, ophiopogon root, batryticated silkworm, hawthornfruit(stir-frying), platycodon root.

98.Qingyan Runhou Pill: belamcanda rhizome, subprostratesophora root, Chinese white olive , tinospora root, dried rehmannia root,scrophularia root, ophiopogon root, anemarrhena rhizome, pulvis cornus bubaliconcentratus, borneol, capejasmine fruit(stir-frying with ginger juice), mutanbark, thunberbg fritillary bulb, batryticated silkworm（stir-fryingwith bran）,white peony root, platycodon root, liquorice.

99.Qingguo Pill: Chinese white olive , honeysuckleflower, scutellaria root, asiatic moonseed rhizome, ophiopogon root,scrophularia root, white peony root, platycodon root.

100.Qinghuozhimai Capsule: green chiretta, capejasminefruit, ophiopogon root.

101.Qingge Pill: honeysuckle flower, forsythia fruit,coptis root, gentian root, belamcanda rhizome, subprostrate sophora root,peppermint, gypsum, sodium sulfate powder, rhubarb(steaming), scrophulariaroot, dried rehmannia root, ophiopogon root, cow bezoare, pulvis cornus bubaliconcentratus, borneol, borax, platycodon root, liquorice.

102.Jianminyanhou Tablet: scrophularia root, ophiopogonroot, dried rehmannia root, isatis root, Chinese white olive , cicada slough,chebula fructus, platycodon root, boat-fruited sterculia seed, peppermint oil,Menthol, liquorice.

103. XuanmaiganjuBuccal Tablet(Granule): scrophularia root, ophiopogonroot, platycodon root, liquorice.

104.Qinghouyan Mixture: scutellaria root, dried rehmannia root,ophiopogon root, scrophularia root, forsythia fruit.

105.Jinming Tablet: dried rehmannia root, sodium sulfatepowder, borax(calcining), artificial cow-bezoare, pearl powder, borneol,scrophularia root, ophiopogon root, red sage root, Menthol, black plum.

106.Biyanling Tablet: subprostrate sophora root, doederlein’sspikemoss herb, barbated skullcup herb, hedyotis, all-grass Japanese raspberry,trichosanthes root, ophiopogon root, scrophularia root, dangshen, poria.

107.Jinsangqingyin Pill: dried rehmannia root, scrophularia root,ophiopogon root, mutan bark, red peony root, dendrobium, scutellaria root,cicada slough, boat-fruited sterculia seed, Indian trumpetflower seed,peppermint, batryticated silkworm（stir-frying with bran）,tendrilleaf fritillary bulb, oriental water plantain rhizom, coixseed(stir-frying), liquorice.

108.Jinsangsanjie Pill: honeysuckle flower, red sage root,isatis root, puff-ball, dandelion herb, peach kernel(remove the peel),safflower, burreed tuber(stir-frying with vinegar), scrophularia root, ophiopogonroot, thunberbg fritillary bulb, oriental water plantain rhizom, membrane ofchicken gizzard(stir-frying), cicada slough, Indian trumpetflower seed.

109.Tiedi Pill(Oral Liquid): ophiopogon root, scrophulariaroot, thunberbg fritillary bulb, snakegourd peel, platycodon root, Chinesewhite olive , inner shell membane of fowl’s egg, chebula fructus, poria,liquorice.

110.Kouyanqing Granule: cochinchinese asparagus root, ophiopogonroot, scrophularia root, honeysuckle flower, liquorice.

Chemical Composition

[1]State Administration Of Traditional Chinese Medicine Material Medical Editorial Board .Chinese Material Medical .Shanghai: Shanghai Scientific And Technical Publishers，1999,22:122(Total 7194)．

[2]Tada A,Shojl J.Studies On The Constituents Of Ophiopogonistuber.Ⅱ.On The Structure Of Ophiopogonin B.Chem Pharm.Bul1.,1972,20(8):1729．

[3]Tada A,Kobayashi M,Shoji J.Studies On The Constituents Of Ophiopogonis Tuber.Ⅲ.On The Structure Of Ophiopogonln D Chem.Pharm.Bul1.,1973,21(2):308．

[4]Watanabe Y,Sanada S,Tada A,Et A1.Studies On The Constituents Of  Ophiopogonis Tuber.Ⅳ. On The Structure Of Ophiopogonin A,B′, C, C′And D′. Chem Pharm.Bul1.,1977,25 (11):3049．

[5]Yang Zhi, Xiao Rong, Xiao Zhuoyin．Studies On The Chemical Constituents Of Ophiopogon Japonicus From Sichuan（I）．West China Journal Of Pharmaceutical Sciences，1987,2(2):57．

[6]Yang Zhi, Xiao Rong, Xiao Zhuoyin．Studies On The Chemical Constituents Of Ophiopogon Japonicus From Sichuan（Ⅱ）．West China Journal Of Pharmaceutical Sciences，1987,2(3):121．.

[7]Adinolfi M,Parrilli M.Terpenoid Glycosides From Ophiopogon Japonlcus Roots. Phytochemistry,1990,29 (5):1696．

[8]Asamo T,Murayama T,Hirai Y,Et A1.Comparative Studieson The Constituents Of Ophiopogonis Tuber And Its Co~Lgeners.Ⅷ.Studies On The Glycosides Of The Subterranean Part Of Ophiopogon Japonicus Ker-Gawler Cv.Nanus. Chem.(2)Pharm.Bul1,1993,41(3):566．

[9]Branke,Thomas J,Haslinger,Et A1.Spirostanol Glycolsidefrom The Tuber Of Ophlopogon Japorficus. Liebigs Ann,1995,(3):587．

[10]Chen Jijun Zhu Zhenlu Luo Shide．Cixi Ophiopogon Japonicus By A And B Structure．The Yunnan Plant Research，2000,22(1):97．

[11tada T,Kasai R,Saitoh S,Et A1.Studies On The Constituents Of Ophiopogonis Tuber.V.Isolation A Novel Class Of Homoisotlavonoids And Determination Of Their Structures.Chem.Pharm.Bul1,1980,28 (5):1477．

[12]Tada T,Kasai R,Saitoh S,Et A1.Studies On The Constituents Of Ophiopogonis Tuber.Ⅵ.Sctures Of Homoisoflavonoids Chem.Pharm.Bul1,1980,28(7):2039．

[13]Kimda Nobu, Nakanishi Hiromiyuki, Kurashi Tadayuki, Et Al. Maimendong (Made In China) Components. Pharmaceutical Journal (Japan).1983,103 (11):1133

[14]Zhu Yongxin, Yan East, Tu Shi. Ophiopogon Japonicus In High Isoflavone Separation And Identification. Pharmaceutical Journal，1987,22(9):679．

[15]Liu Chengji, Once Quan, Ma Bei. Studies On The Chemical Constituents Of Ophiopogon Japonicus.Chinese Herbal Medicines ，1988,19(4):10．

[16]Zhu Yongxin, Liu Linzhe, Wang Wei, Et Al. Studies On The Chemical Constituents Of Ophiopogon Japonicus. China Journal Of Chinese Materia Medica，1989,14(6):359．

Pharmacological Effects

[1]Yu Kaixi. Shanghai Journal Of Traditional Chinese Medicine，1985,(12):3．

[2]Gao Guangyou, Li Chuanxun, Duan Peng, Etc.Hemodynamic Effects Of Water Soluble Extract Of Liriope Spicata Lour On Anesthetized Cats．China Journal Of Chinese Materia Medica, 1989,14(9):552．

[3]Wei Dehui.Chinese Herbal Medicines ，1982, 13(9):411．

[4]Mo Positive Discipline, River Guangchi, Jean Blue, And So On. Pharmacological Studies On The Active Constituents Of Ophiopogon Japonicus．West China Journal Of Pharmaceutical Sciences，1991,6(1):13．

[5]Gao Guangyou, Li Chuanxun, Duan Peng, Etc.Effects Of "Ophiopogon Injection" On Hemodynamics In Rats Of Heart Failure Following Myocardial Infarction．Shanghai Journal Of Traditional Chinese Medicine，2007,41(7):56．

[6]Gu Shuanglin, Xu Naishan, Jike, Etc.Ophiopogon Japonicus On Experimental Myocardial Infarction And Myocardial Hypoxia Submicroscopic Structure Influence.Shanghai Journal Of Traditional Chinese Medicine, ，1983,(7):44．

[7]Gao Guangyou, Song Xiaoliang, Ye Li-Hong, Etc.Effects Of Total Aminoacid Of Liriope Spicata Lour On Experimental Myocardial Ischemia.Chinese Pharmacological Bulletin，1993,9(4):281．

[8]Zheng Guoqin, Feng Yi, Xu Desheng, Et Al.Protective Effect Of Ophiopogonis Polysaccharide Mdg-1 On Experimental Myocardial Ischemic Rats.Chinese Journal Of Integrated Traditional And Western Medicine， 2007,27(12):1116．

[9]Chen Min. Chinese Journal Of Pharmacology,1990,11(2):161．

[10]Yu Boyang, Yin Xia, Xu Guojun, Et Al..Hubei And Zhejiang Ophiopogon Maidong On Quality Of Immune Activity. China Journal Of Chinese Materia Medica, 1991,16(10):584．

[11]Han Fengmei, Liu Chunxia, Et Al. Radix Liriopes Polysaccharide On Immunity In Mice.China Journal Of Traditional Chinese Medicine And Pharmacy, ，2004,19(6):347．

[12]Jiangtian Young Japanese Journal Of Pharmacology，1971,67(6):223．

[13]Zhang Weixing．Chinese Herbal Medicines ，1993,24(1):30．

[14]Qiu Baohua, Li Ruiman. Polysaccharide In Ophiopogon Japonicus On Gestational Diabetes Mellitus Rats The Effect Of Glucose. Journal Of Jinan University (Medical Sciences)2008,29 (4):367．

[15]Li Ruiman, Qin Jia, Pei Zhaohui.Ophiopogon Japonicus In Patients With Gestational Diabetes Mellitus Insulin Resistance Effect And Mechanism Of The Fourth Military Medical University，2008,29(5):410．

[16]Gao Changkun, Gao Jian, Xu Xianxiang.Ophiopogon Japonicus Total Saponins On Experimental Hyperglycemia Mice Hypoglycemic Effect．Chinese Journal Of Laboratory Medicine，2007,L3(5):33．

[17]Huang Ketai．Chinese Herbal Medicines ，1992,23(10):538．

[18]Huang Ketai, Liu Zhongshen, Yu Zheda, Et Al. Research On Comprehensive Development And Utilization Of Dwarf Lilyturf Root．China Journal Of Chinese Materia Medica, 1992,17(1):21．

[19]Wang Zhaojing Luo Dianhui.Water Soluble Active Polysaccharide Opa Purification And Antioxidant．Modern Traditional Chinese Medicine，2008,28(5):77．

[20]Yang Renxuan, Deng Jinfeng, Lu Songhua, Etc.Effect Of Dwarf Lilyturf Tuber Saponin On Chondrocyte Survival,Proliferation And Resist Oxygenation．Journal Of Liaoning University Of Traditional Chinese Medicine, 2007,9(5):36．

[21]Liu Jieshu．Experimental Study On The Anti-Aging Effect Of Dwarf Lilyturf Tuber Injection．China Pharmacy，2006,L7(23):1774．

[22]Chen Yong, Wang Boxiang, Wen Set Pu, Etc.．Effects Of Heat-Clearing Herbs And Yin-Nourishing Herbs On Gastroitestinal Motility．Pharmacology And Clinics Of Chinese Materia Medica，1992,8(3):17．

[23]Zhao Bo,Wu Chang-Jian,Gao Hong,Et Al.Sedative And Hypnotic Effect Of Ophiopogon Japonicus On Mice．Journal Of Xianning College(Medical Sciences), 2008,22(4):282．

[24]Wu Zhirong, Liu Zhongfang, Feng Jumei, Ophiopogon Injection Study.Proprietary Chinese Medicines，1981 ,(11):12．

[25]Gui Yi．Chinese Herbal Medicines ，1984,15(3):317．

[26]Yu Boyang, Yin Xia, Zhang Chunhong, Etc．Immunity Study On Polysaccharide From Tuberous Roots Of Ophiopogon Japonicus (L.F.) Ker-Gawl.．Journal Of China Pharmaceutical University, 1991,22(5):385．

[27]Liaoyanxiong. Northwest Veterinarian Institute School Magazine，1953,(4):5．

[28]Nakanishi Hiromiyuki. Pharmaceutical Journal (Japan),1987,107(10):780．

[29]Yu Boyang, Yin Xia, Rong Zu-Yuan, Et Al．Liriope Saponin C In Pharmacological Research.Journal Of China Pharmaceutical University, 1994,25(5):286．

[30]Toda Shizuo .Foreign Medicine（Chinese Medicine Part），1989,11(6):38．

[31]Hu Yan-Ping, Song Jie, Wang Xin, Et Al．Genotoxicity Study Of Radix Ophiopogonis Decoction．Chinese Journal Of Information On Traditional Chinese Medicine,2009,16(7): 38．

Clinical Research:

[1] Yan Tingting. Ophiopogon To Shao Tang In Treating Sjogren Syndrome: Clinical Observation Of 20 Cases.Journal Of Nanjing University Of Traditional Chinese Medicine, 2008,24（1）：63-65.

[2] Li Ziqiang Maidong Decoction In Treating 43 Cases Of Chronic Pharyngitis.China’S Naturopathy, ，2003,11（2）：45.

[3] Xu Caixia Ophiopogon Japonicus With Clothes In Treatment Of Children Chronic Pharyngitis Clinical Observation. Tianjin Journal Of Traditional Chinese Medicine,200,17(2):46.

[4] Li Guangjing And Radix Ophiopogon Japonicus In Treatment Of 15 Patients With Intractable Hiccup. Journal Of Practical Traditional Chinese Medicine,2004,20(2):75.

Toxicology

[1]Wei Dehui, Etc.Chinese Herbal Medicines 1982.13(9):41

[2]Wu Zhirong, Etc.Proprietary Chinese Medicines,1981,(11):

[3]Gui Yi, Etc.Chinese Herbal Medicines ,1984,15(3):17