Sebiferm Sapium Bark - China and Thailand medicinal plants professional database

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[English Name]	Sebiferm Sapium Bark
[Chinese Name]	乌桕
[Pinying Name]	Wujiu
[Latin Name]	Sapii Sebiferi Cortex
[Genera]	Euphorbiaceae
[Efficacy]	xiexiayao
[Pictures]	Plant picture	Drug picture

[Alias]
[Source]
[Plant morphology]
[Distribution]
[Gathering and processing]
[Characteristics]
[Ecology]	It prefers light,warm climate,and the thick、fertile 、rich moisture soil, no strong cold resistance, can grows in the area with mean annual temperature above 15℃，annual rainfall above 750mm. Good adaptability to the soil,it can grows in the river bank alluvial soil、plain paddy soil、low hills clayed red soil and moutain red yellow soil.It grows well in alluvium soil with thick and fertile.It grows vigorously in the soil with good water condition.It can resistant to the short-term water and drought,salt content is more than 0.3%.Life span is long. Immature trees start to fruit in 4 to 5 years, come into full productive age after 10 years, consenescence gradually after 60 to 70 years,grows persistently more than 100 years in a good site condition.
[Chemical composition]
[Pharmacological activities]	1. The extracts isolated from Sapium sebiferum leaves with different solvents exhibit antibacterial activity, and the strongest antibacterial activity came from ethyl acetate soluble fraction^[2]. 2. The extracts of Sapium sebiferum leave has significant analgesic and anti-inflammatory effect on animal models and shows obviously dose-effect relationship^[3]. 3. The extracts of Sapium sebiferum leave also exhibit other pharmacological effects such as reducing blood pressure, causing inflammation, promoting the proliferation of tumor and so on^[1,4].
[Clinical trial]	1. Postpartum perineal wound infection: 430 cases were treated with wujiu(Sebiferm Sapium Bark) Decoction from fresh leaves and stalks repeated washing, daily 3 times, for 7 to 21 days, until the wound granulation and wound healing.Results showed that 400 cases were cured, the cure rate was 93.02%^[1] . 2. Snake bite: 66 cases whose wound did not collapse were treated with wujiu(Sebiferm Sapium Bark) cream (fresh wujiu(Sebiferm Sapium Bark) leaves ,added appropriate amount of liquor, a little flour ) before detoxification..Results showed all patients were healed, the average healing time was 5 days ^[2]. 3. Acute glomerular nephritis: 32 cases were treated with wujiushenkangbao doctotion (wujiu(Sebiferm Sapium Bark), daodiaobi root(Fall hanging pen root), yangtiteng(Bauhinia glauca),baihuaguizhenquan root(White ghost light group root),yingbupu root(spiny aralia)), 3 times a day. Results showed that besides 1 cases of nephrotic syndrome treated with were invalid, the remaining of 31 cases were cured, the cure rate was 96.9% ^[3] .
[Properties]
[Medical and other Uses]
[Dosage]
[Cautions]
[Traditional usage]	1. Clove sore 2. Eczema, urticaria, bromhidrosis and scab 3. Traumatic injuries 4. Poisonous snake bites 5. Tympanties 6. Stranguria and puffiness of the body 7. Urinary obstruction
[Toxicological studies]
[Pharmaceutical preparations]
[References]	Pharmacological actions: [1] Nanjing TCMU. Chinese medicine dictionary. Shanghai: Shanghai Science and Technology Press, 2006:665. [2] YE Zhou. Studies on the antibacterial activity of extracts from Sapium sebiferum leaves. Journal of Fujian College of Forestry, 2007,27(3):231-235. [3] HUANG Bin-xue, HUANG Zeng-qiong, XU Xiao-lin, et al. Analgesic and anti-inflammatory effect of extract of Sapium sebiferum leaves on animal model. Chinese Traditional Patent Medicine, 2004,26(6): 48-51. [4] Nanjing TCMU. Chinese medicine dictionary. Shanghai: Shanghai Science and Technology Press, 2006:76. clinical test: [1]lin jingqin，etc. Clinical observation on Postpartum perineal wound infection treated with wujiu(Sebiferm Sapium Bark).guangdong medicine，1999，20(3):216 [2]dongpeng，etc. Snake bite treated with wujiu(Sebiferm Sapium Bark) cream in 66 cases.chinese community doctors，2002，18(3):41 [3] Liangbishen. Acute glomerular nephritis treated with Chinese medicine in 32 cases. Youjiang Medical Journal，2001，29(6):532