1. Bacteriostasis: Decoction show a significant depressant effect to Golden Staphylococcus\Staphylococcus epidermidis\hemolytic streptococcus\micrococcus catarrhalis, and when it combine with trimethoprim show a strengthen antibacterial action. It’s ethanol extract can kill Leptospira and anti HSV-Ⅰeffect[1,2].

2. Cholaneresis and Hepatoprotection: Dandelion parenteral solution or ethanol extract show a significant increase bile volume in rat model. It can relieve acute liver injury induce by antiendotoxin in rat model[3,4].

3. Anti Gastric Injury: Water extract may through inhibit gastric acid secretion and step-up the PGE2 content in gastric mucosa make Helicobacter pylori darkening and ulcer healing[5,6].

4. Antitumor: It’s triterpenes compounds has different degree to inhibit second stage induce skin cancer in mice model. And it’s polysaccharides show a similarity anticancer mechanism with Lentinan[7].

5. Other Effects: It can increase female steroid hormone level, galactogogue action, Diuresis effect, improvability cholesterolemia, adjust isolated frog heart and ex vivo artery and so on. But the mechanism of action still pending[8].

1. Pediatric constipation: 30～60g fresh herbs were boiled with water and taken by patients, one prescription a day. The cured rate was 98%, no toxic and side effects, seldom relapse happened. Patients with Qi and blood deficiency were not allow to used[1].

2. Postpartum galactostasis: 83 cases of patients were treated with Pugongying decoction, one prescription a day, three days as one course of treatment. Analgesic-antipyretic drugs were given at the same time if patients' temperature over 38℃. Results showed that 55 cases were cured, 26 cases' condition had improved, two cases were invalid, the overall effective rate was 97.06%^[2].

3. Hordeolum: 30g Pugongying and 15g Jinyinhua were boiled with water, the decoction that boiled fist time was used for oral administration and the second decoction was used for lotion. There 120 cases of patients were treated, 46 cases were cured at the first day, 40 cases were cured at the second day, ten cases at the third day; 20 cases had effects, four cases were invalid, the overall effective rate was 96.7%[3].

4. Viral hepatitis A: 30g fresh Pugongying and Cheqiancao were used to prevent the infection of viral hepatitis A. 126 people were given the drugs within 26 days, only 11 people were infected, the morbidity was 8.7%. significant difference was obtained when compared to the group without using the drugs[4].

Pharmacologic Actions:

[1] Liu Xiguang, Hu Yuanyang, He Huajun, et al. Chinese Journal of Integrated Traditional and Western Medicine, 1986,6(12):737．

[2] Zheng Minshi. Chinese Journal of Integrated Traditional and Western Medicine, 1990,10(1):39.

[3] Shi Hegao. Journal of Traditional Chinese Medicine, 1979,(12):55.

[4] Ling Yun. Beijing: Beijing Medical University, 1996:4.

[5] Ma Fengyou. Acta Chinese Medicine and Pharmacology, 1991(1):41．

[6] You Chunlai, Han Zhaofeng, Zhu Dan, et al. Pharmacology and Clinics of Chinese Materia Medica, 1994,10(2): 23．

[7] Yi Yue. International Journal of Traditional Chinese Medicine, 1998,20(4):63．

[8] Weng Xiaogang. International Journal of Traditional Chinese Medicine, 2001,23(6):346．

Clinical trial:

 [1]Zhao Chengxin. Dandelion Possesses the Function of Pediatric Hot Poison Constipation. Jilin Journal of Traditional Chinese Medicine,2007,27(10):48.

[2]Ji Hui.Pugongying soup in treatment of Postpartum Milk Deposition in 83 cases, Tianjin Journal of Traditional Chinese Medicine,2007,24(3):247.

[3]Wang Letian. Combining Dandelion with honeysuckle in treatment of hordeolum, ACTA Universitis Medicinalis Anhui,1996(3):245.

[4]Shen Yongan. Fresh Traditional Chinses herbs in Prevention of Vlral hepatltlsA, Chinese Journal of Digestology,1998,6(特刊7):65.

[5]Cai Wenke.Fresh Dandelion in treatment of acute mastitis in 20 cases. Sichuan of Traditional Chinese Medicine,1999,17(11):37.

[6]Huang Jun.Baihegongying soup in treatment of Chronic Yin deficiency type atrophic gastritis. New Chinese Medicine,1994(6):45.

[7]Huang Junyou. Integrated Chinese and western medicine in treatment of wart in 64 cases.   Journal of External Therapy of Traditional Chinese Medicine,1999,8(3):26.

[8]Yang Yongdong. Observation of Effect of Dandelion cooperating (131)I in treatment of Graves Merger Exophthalmia in 175 cases. Fujian Medical Journal,2004,26(5):110-111.

[9]Ding Jingyuan. Synecdoche the Clinical Application of Fresh Dandelion. Hunan Journal of Traditional Chinese Medicine,2004,20(1):58.