Location:Home > Cherokee Rose Fruit > [Chinese]
[English Name] Cherokee Rose Fruit
[Chinese Name] 金樱子  
[Pinying Name] Jinyingzi  
[Latin Name] Rosae Laevigatae Fructus  
[Genera] Rosaceae
[Efficacy] shouseyao
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology] It grows in waste moutain and field which is plenty of stone.  
[Chemical composition]  
[Pharmacological activities]

1. Lacvigata michx polysaccharide had some antimicrobial activities, for example, to Escherichi coli, Salmonella.paratyphi, Staphy lococcus cremoris and so on, and also had some anti-inflammatory activities[1].

2. Fructus Rosa Laevigata can decrease serum glucose and triglyceride levels in NewZealand white rabbit[2].


3. Rosa Laevigata Mickx has distinctive effect on anti-oxidation. It could significantly scavenge superoxide anion, inhibit murine erythrocyte hemoyisis and lipid peroxidation in mouse liver homogenate[3]

4. Rosa Laevigata Mickx can protect kidney of streptozotocin-induced diabetic rats. The mechanism may be partly mediated by inhibit ing TGF-β1 and type collagen overexpression in kidney[4]. The water extract of Rosa laevigata can decrease the frequency, prolong the interval of urination, increase the quantity of eacn urination, inhibit the automatic contraction of isolated rabbit jejunal smooth muscle and antagonize the spasmodic contraction aroused by acetylcholine and barium chloride of isolated rabbit jejunal smooth muscle, and isolated vesical smooth muscle of mouse, and antagonize reaction of contractility aroused by noradrenalin on isolated thoracic aorta strips of rabbit[5].


5. Polysaccharide from Rosa laevigata michx can enhance the immune reaction in mouse and has immune modulation function[6].

 
[Clinical trial]

1. Older incontinence24 cases patients were treated with Jinyingzi(Cherokee Rose Fruit) docotion. Results showed that 14 cases had significant effect, accounting for 58%7 cases had effect, accounting for 29%3 cases were invalid, accounting for 13%. The overall effective rate was 87% [1]

2. Chronic recalcitrant diarrhea Jinyingzi(Cherokee Rose Fruit)binglan(Semen Arecae)docotionJinyingzi (Cherokee Rose Fruit) 45g, Binglan(Semen Arecae) 3g, Zhishi(Fructus Aurantii Immaturus)3g, Wuzhuy (Evodia rutaecarpa) 6g, Buguzhi(Malaytea Scurfpea Fruit) 9g. Two weeks as one course of treatment. Results showed thati in 50 cases of the treatment group, 34 cases patients were cured,9 cases had Signifi- cant effect, 4 had effect,3 cases were invalid, the Clinical cure rate was 68%,the overall effective rate was 94% [2]

3. Nocturnal enuresisJinyingzi(Cherokee Rose Fruit)binglan(Semen Arecae) granules, match with acupuncture. 15 days as one course of treatment. After treated with one course of treatment . Results showed 129 cases patients were cured,3 cases improved,4 cases were invalid,The overall effective rate was 97.61% [3]

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]

1. Bleeding induced by incised injury

2.Chronic dysentery, tuberculosis of intestine

3.Nocturnal emission and prospermia, morbid leucorrhea caused by weakness

 
[Toxicological studies]  
[Pharmaceutical preparations]  
[References] Pharmacological actions:

[1] ZHANG Ting-ting; PAN Ji-hong; NIE Liu-wang, et al. Studies on the ant-microbial and anti-inflammatoryactivities of Rosa Lacvigata michx polysaccharides. Journal of Biology, 2005,22(2):41-42.

[2] ZHANG Qiu-ju; YIN Wei-dong; Xi Shou-min, et al. Effects of Fructus Rosa Laevigata and Membrance of Chickens Gizzard on Serum Glucose,Lipid and Insulin Levels in Rabbits. Chinese Journal of Arterial Lerosis, 2003,11(3):227-229.

[3] ZHAO Yun-tao, GUO Xing-ming, LI Fu-zhen. Anti-oxidative activity of polysaccharide from Rosa Laevigata Mickx. Journal of Biology, 2003,20(2):23-24.

[4] ZHOU Yu-juan, LIAO Qian-jin, Zhang Qiu-ju, et al. Experimental Study of Rosa Laevigata Mickx in Kindey of Streptozotocin-Induced Diabetic Rats. Journal of Nanhua University(Medical Edition), 2007,35(3):332-335.

[5] Lu Yin, Sun Zhi-guang; Xu Hui-qi, et al. Effect of Jinyingzi (Rosa laevigata) Aqueous Extract on Urinary System. Chinese Traditional and Herbal Drugs, 1995,26(10):529-531.

[6] ZHANG Ting-ting, NIE Liu-wang, LIU Ai-min, et al. Studies on Immune Activities of Rosa Laevigata Michx Polysaccharide. Chinese Journal of Experimental Traditional Medical Formulae, 2005,11(4):55-58.
clinical test:

[1] Zhang chun-lin. Old incontinence treated with Jinyingzi (Cherokee Rose Fruit) root in 24 cases. Journal of Practical Traditional Chinese Medicine200319(9)470

[2] Ligang.Efficacy observation on Chronic recalcitrant diarrhea treated with Jinyingzi (Cherokee Rose Fruit)binglan(Semen Arecae)docotion in 50 cases.Journal of New Chinese Medicine200638(2)34

[3] Ni Zhao-hai. Nocturnal enuresis treated with Jinyingzi (Cherokee Rose Fruit)granules, matching with acupuncture in 168 cases.Journal of Practical Traditional Chinese Internal Medicine200721(2)107.