[English Name] | Beautyberry leaf | |
[Chinese Name] | 紫珠 | |
[Pinying Name] | Zizhu | |
[Latin Name] | Callicarpa bodinieri Purplepearl | |
[Genera] | Verbenaceae | |
[Efficacy] | zhixueyao | |
[Pictures] | Plant picture | Drug picture |
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[Plant morphology] | ||
[Distribution] | ||
[Gathering and processing] | ||
[Characteristics] | ||
[Ecology] | It is tropical plant,prefers warm and moist,is afraid of wind and draught, mean annual temperature between 15 to |
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[Chemical composition] | ||
[Pharmacological activities] |
1. Callicarpa bodinieri Purplepearl exhibit actions on promoting blood clotting, contracting vessel and increasing platelet number[1-3]. 2. Callicarpa bodinieri Purplepearl has the inhibiting effect on the growth of bacteria such as escherichia coli, shigella dysenteriae, staphylococcus aureus, typhoid bacillus, hemolytic streptococcus, pseudomonas aeruginosa and so on[4]. 2. |
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[Clinical trial] | 1. Bleeding:(1) upper digestive tract hemorrhage ①305 cases were treated with zizhu(beautyberry leaf) for frozen lavage. Among duodenal ulcer of 190 cases, gastric ulcer of 32 cases, gastric anastomotic ulcer of 7 cases, stress ulcer of 5 cases ,chronic gastritis and duodenitis of 42 cases, gastric mucosa prolapse of 4 cases, unknown causes of25 cases. Results showed that in the mild symptoms (131 cases),125 cases were cured, 1 case was effective, 5 cases were invalid and the average time for stool occult blood tests turning negative was 3.6d. In the Moderate (114 cases), 109 cases were cured, 1 case was obvious effective, 2 cases were effective, 2 cases were invalid, the average time for stool occult blood tests turning negative was 4.3d. In the Severe (60 cases), 50 cases were cured, 2 cases were obvious effective, 1 cases were effective, 7 cases were invalid, the average time for stool occult blood tests turning negative was 4.7d.The total cure rate was 93.1%, the efficiency was 95.4% [1]. ②20 cases of esophageal variceal bleeding caused by cirrhotic portal hypertension after the failure of three tube compression hemostasis and posterior pituitary protamine hemostatic were treated with zizhu(beautyberry leaf) 60g, fried thick, injected into stomach. 19 cases were treated by gastric perfusion, the other 1 case by oral.Results showed that 17 cases were stopped bleeding in 24h, accounting for 85%;3 cases were invalid, accounting for 15%[2].⑵bleeding of operation: ①bleeding after tooth extraction: 500 cases (800 teeth)were Observed, After tooth extraction, zicao powder sprinkled wound, the efficient rate was 99% [3]. ②bleeding during operation: 53 cases were treated with zicao water extractives , made into absorbable hemostatic gauze and used in clinical departments, of operation process of hemostasis. Results showed that large-scale operation of 35 cases, medium-sized operation of 12 cases, small-sized operation of 6 cases. It can stopped bleeding subcutaneous tissue in 1~2min, basically without hemostatic forceps Where a vessel diameter less than 0.5mm [4]. ③bleeding and pain after tonsillectomy: zizhu(beautyberry leaf) 1000g, meipian5g, juhua(Chrysanthemum)250g, added sesame oil 1000ml. After tonsillectomy, zimeiju oil agent was putted in the tonsillar fossa wounds. In 58 cases, 41 cases were excellent effective [5].④Functional uterine bleeding : 40 cases were treated with zizhu(beautyberry leaf), direngen(Melastoma dode candrum Lour), fangtianhua(Urena procumbens) each30g and took it in first days of menses. 1 agent Daily, took 3 agents continually, in order to consolidate the curative effect, it can take 3~6 agent. Results showed that 33 cases were followed up, of which 16 cases were cured, 14 cases were effective, 3 cases ineffective, it took at least 3 agent to the 20 agent [6]. 2. Hemorrhoid: 614 cases of hemorrhoid, mixed hemorrhoid and annular hemorrhoid were treated with Zizhu (beautyberry leaf) kuzhi injection (zichucao (beautyberry leaf) 250g, alum 3g, procaine 1~2g) for injection .Results showed that 596 cases were cured, the curative rate was 97.1%. The curative rate of internal hemorrhoid, mixed hemorrhoids and annular hemorrhoid was 99.6%, 95.1%, 93.2% respectively.92.53% of the patients cured in one time [7]. 3.Burn:20 cases were treated with Zizhu(beautyberry leaf) grinded into powder for external use. 1 time daily or alternate-day. Results showed that the patients of the superficial II degree burn scabbed after 2~3 times and scabbed off after 2~3days; the patients of the deep second degree burn scabbed after 3~7 times and scabbed off after 2~5days. There was no scar after healing [8]. 4.Gynecological inflammation: 78 cases of cervicitis ,Vaginitis( including general vaginitis、beads bacterium vaginitis ) were treated with zizhu(beautyberry leaf) . Results showed that 38 cases were cured, 33 cases improved, the effective rate was 91% [9]. |
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[Properties] | ||
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[Traditional usage] |
1.Hemoptysis 2.Hemoptysis induced by pulmonary tuberculosis, hemorrhage due to gastroduodenal ulcer 3.Bleeding caused by gastric ulcer 4.Bleeding from aperture or subcutaneous tissue 5.Unstopped bleeding after tooth extraction 6.Functional metrorrhagia 7.Thrombocytic purpura 8.Bleeding caused by trauma 9.Internal injury bleeding 10.Swelling and pain due to sprain 11.Upper respiratory tract infection, tonsillitis, pneumonia, bronchitis 12.Reddish eyes 13.Carbuncle, pharyngitis, snake bite, rabies 14.Vaginitis, cervicitis 15.Scrofula, goiter |
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[Toxicological studies] | ||
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[References] |
Pharmacological actions: [1] Promotion group of Chinese Herbs of Hangzhou first hospital. The mechanism of Callicarpa bodinieri Purplepearl on hemostatic and clinical application. 1971:3. [2] Chinese people's Liberation Army 459 hospital. Selections of medicine and health research experience exchange materials. 1972:156. [3] research data of [4] Chinese people's Liberation Army 468 hospital. The species, cultivation, preparation and application of Callicarpa bodinieri Purplepearl. 1970:2. [1] Qiu heming,etc.China Journal of Chinese Materia Medica,1988.13(8):48. [2] Zhang zhihong.Jiangsu Medical Journal.1978. (3):9. [3] Dentistry in people's hospital, Haikou city, Guangdong province .New Medicine. 1971,(10):45. [4] The first hospital in fuzhou.Chinese herbal medicine communication.1971.(1):21. [5] Han wenxian.Chinese Journal of Integrative Medicine.1986.(3):305. [6] Herbal room in health center, yuhu area, wenchen town, Zhejiang province .Chinese Journal for Clinicians.1975. (2):29(79). [7] Military fuzhou general hospital.People Military Surgeon.1975.(2):57. [8] Wang ligang.Chinese Journal for Clinicians.1975.(4):10(176). [9] Hainan area of Guangdong people’s hospital of gynecology.New Medicine. 1971. (6.7):45. |