[English Name] | Copperleaf Herb | |
[Chinese Name] | 铁苋菜 | |
[Pinying Name] | Tiexiancai | |
[Latin Name] | Acalyphae Australis Herba | |
[Genera] | Euphorbiaceae | |
[Efficacy] | Antipyretic drug | |
[Pictures] | Plant picture | Drug picture |
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[Alias] | ||
[Source] | ||
[Plant morphology] | ||
[Distribution] | ||
[Gathering and processing] | ||
[Characteristics] | ||
[Ecology] | It mostly grows in middle and lower basin of the Yellow River basin and all over south of the Yangtze river,and wilderness、wetter area beside road. | |
[Chemical composition] | ||
[Pharmacological activities] |
1 Antibacterial capability:Escherichia coli, Staphylococcus aureas, Salmonellacholerae-suis, have some Certain inhibition effect, particularly have the bestinhibition effect of Staphylococcus aureas [1,2]; the effect of extracted waterwas 60 % better than alcohol extraction water. The inhibition concentration was62.50 mg·mL-1, 15.62 mg·mL-1, 125.00 mg·mL-1expectively [3]. So it is considered the extraction of ethyl acetate is thefrom Acalypha australis L. is more effective concentration of the effect site[4]. We take advantage of the organic solvent, extraction technique, divide theamaranth iron extraction water having the better antibiosis action in to fourpolarity parts of petroleum benzine, chloroform, acetoacetate, and n-butanol[5]. 2 Anti-inflammatory: Acalypha decoction inprevention and treatment of trinitrobenzene sulfonic acid induced ulcerativecolitis in rats [6]. The index SOD andGSH-Px increased and MDA reduced significantly in high-and moderate-copperleafdecoction groups compared with the model group [7]. The production of NO theactivity of iNOS reduced significantly in high-and moderate-copperleafdecoction groups compared with the model group [8]. RT-PCR results demonstratedthat the expression of iNOS mRNA was significantly inhibited in TNBS-inducedulcerative colitis rats after being treated with moderate-dosage copperleaf.Acalypha australis L. has antioxidative and antinitrosative effects which isprobably one of the mechanism of copperleaf for treating UC [9]. 3 Antidiarrhealeffect: Acalypha can inhibit salivationand diarrhea, the effective ingredients of diarrhoea, in addition to the gallicacid, geraniin, caffeoylmalic acid should also be regarded as effectiveingredients [9] 4 Hemostatic: Acalypha promoted platelet adhesion and accumulation, beneficial to theformation of bthrombus, decrease the action of antithrombin, increase thecontent ofα2-MG,reduce the fibrinolysis activity and promotethe blood coagulation. Thehemostatic mechenism was related to increasing plateletcount, promoting itsfunction, inhibiting fibrinolysis system [10]. 5 Antiasthmatic Effects: Gallic acid extracted Acalypha austrolis L. significantly antagonizedbronchoconstriction, and the efficacy can be maintained for 120 minutes [11]. |
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[Clinical trial] | 1. Bacterium dysentery enteritis: 2. Amebic dysentery: 100~ 3. Ileotyphus: 4. Upper gastrointestinal hemorrhage: 105 cases of patients were treated with Xueyu tablet, 3~4 times a day, 4 tablet for each time. Results: 101 cases stopped hematemesis and fecal occult blood test conversed negative, the effective rate was 96.1%. |
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[Properties] | ||
[Medical and other Uses] | ||
[Dosage] | ||
[Cautions] | ||
[Traditional usage] |
1. Poisonous snake bite 2. Amebic dysentery 3. Dysentery , enteritis 4. Fistula 5. Hematemesis, hematochezia, and hematuria 6. Malaria 7. Hypogalactia 8. Infantile malnutrition 9. Pediatric dyspeptic diarrhea 10. Pediatric abdominal distension, swelling of testis |
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[Toxicological studies] | ||
[Pharmaceutical preparations] | ||
[References] |
Clinical trial: [1] |