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[English Name] White Mulberry Root-bark
[Chinese Name] 桑白皮  
[Pinying Name] Sangbaipi  
[Latin Name] Cortex Mori  
[Genera] Moraceae
[Efficacy] zhikepingchuanyao
[Pictures] Plant picture Drug picture
   
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]      It prefers warm and moist climate,resistants shade slightly.It starts sprouting when the tempareture above 12.Growth optimal temperature is between 4 to 30, is inhibited when more than 40,stops when less than 12It resistants to drought,doesn’t resistant to waterlogging,resistants to barren.Strong adaptability to soil.  
[Chemical composition]  
[Pharmacological activities]

1. The extracts of Cortex Mori processed by water, ethanol, methanol, n-butyl alcohol and diethylether could lower the blood pressure of dogs, rabbits and rats[1-14].

2. The extracts of Cortex Mori processed by ethanol and n-butyl alcohol have a excitatory effect on the stomach, intestine and uterus of dogs and rabbits[4,5].

3. The extracts of Cortex Mori processed by water and n-butyl alcohol exhibit effects on nervous system such as abirritation, relieving cough, hypothermia and sedative action[7].

4. The extracts of Cortex Mori processed by water and n-butyl alcohol also has diuretic effect on rabbits and rats[6-7].

5. The water extract of Cortex Mori has a anti-bacteria, anti-tumor actions and the methanol extract could lower the blood sugar of mice induced by alloxan[15-21].

 
[Clinical trial]

Epistaxis: fresh or dried sangbaipi (White Mulberry Root-bark) root decocted with water, 3 times a day, usually 3 days and more, in order to consolidate the curative effect and relapse prevention, and then continued 1 week. The treatment of epistaxis of pneumophila heat inverse type in 115 cases, all were cured [1] .

 
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage]

1.       hyperactivity of lung heat with quick dyspnea and cough in infant

2.       Water retention in the lung with distention and quick dyspnea

3.       Severe cough, or spitting fresh blood

4.       Pain on waist and feet, spasm of tendons and meridians, difficulty in extension and flexion, and sitting and lying

 
[Toxicological studies]  
[Pharmaceutical preparations]  
[References] Pharmacological actions:

[1] Fu liuxijiunan. Japanese Physiological Journal, 1938,3(2):172.

[2] Du biangang. Japan Central Revuo Medicine, 1942.77:17.

[3] Ling muwenzhu. Japan Central Revuo Medicine, 1944.86:14.

[4] Zhong cunyanmei. Japanese Pharmacological Journal, 1960,56(1)44.

[5] Tui cunyanmei. Japanese Pharmacological Journal, 1960,56(3)704.

[6] Rao Man-ren. chinese medical journal, 1959,45f(1)67.

[7]Yamatake Y. Japan J Pharnacol, 1976,26(4): 461.

[8] Xu Chang-shan. Japan Central Revuo Medicine, 1966,219:498.
[9] Feng Ke-yu, Liu Guo-xiong, Zhang yi. Effects on lowering blood pressure and toxicity of the ethanol extract isolated from Cortex Mori. New Medicine Journal, 1974,(03):43.   

[10] Li Chang-ge. Effects on lowering blood pressure of the components isolated from Cortex Mori. Foreign Pharmacology Journal, 1981,2(1):44.

[11] Yin Hui-xian. Structure of Moracenin A with blood pressure lowering effect isolated from Cortex Mori. Foreign Pharmacology Journal, 1981,2(02):21.

[12] Yin Hui-xian. The active constituent with blood pressure lowering effect of Cortex Mori——Moracenin B. Foreign Pharmacology Journal, 1981,2(06):21.

[13] Yin Hui-xian. The new flavonoids derivatives——Kuwanon G isolated from Cortex Mori. Foreign Pharmacology Journal, 1981,2(02):20.

[14] Nornura T,el al. Foreign Pharmacology Journal, 1982,2(4):23.

[15]Nornura T,et aI.C A,979,90:55116f.

[16] Micrology staff room of Nanjing pharmaceutical college. Anti-bacteria effect of 295 kinds of Chinese medicine. Journal of Nanjing pharmaceutical college, 1960,(5):10.

[17] I.ee HK,etal.CA.1966,65:I1009d.

[18] Zuo Tengzhaoyan. Chinese Prescription Rearch, 1979,(2):5l.

[19] Mu cunshanxing. Foreign Pharmacology Journal, 1987,9(2):l07.

[20] Chen Ji-min. Wuhan Chinese medicine, 1958:68.

[21]Hikino H,rt al.PlantaMed,1985,(2):159.

clinical test:

[1] Yang shucheng. Epistaxis treated with sangbaipi(White Mulberry Root-bark). Journal of Medical Theory and Practice19947(12):38