Location:Home > Atractylodes Rhizoma > [Chinese]
[English Name] Atractylodes Rhizoma
[Chinese Name] 苍术  
[Pinying Name] Cangzhu  
[Latin Name] Rhizoma Atractylodes  
[Genera] Compositae
[Efficacy] huashiyao
[Pictures] Plant picture Drug picture
   
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]     It grows in the area at the altitude between 50 to 1900 metres,grows in dry land of hillside or grass,has very strong viability.It can be planted both in waste moutains and  unfertile land,prefers cool climate,sandy soil with good drainagelow  groundwater levelloose soil structure and rich humus.It avoids low-lying land,because of root easily in a mass when waterlogged.  
[Chemical composition]

The rhizome contains volatile oil: 2-carene, 134567-hexahydro-255-trimethyl-2H-2,4α-ethanonaphthalene, β-maalinene, chamigrene, caryophyllene, elemene, humulene, selinene, patchoulene, 19-aristolodiene, guaiol, elemol, atractylone, seli-na-4(14),7(11)-diene-8-one, atractylodin, hinesol, β-eudesmol[12], α-bisabolol, hinesol [8], atractyoldinol, acetylα-tractylodinol[10];

furlade-hyde[3], 3β-acetoxyatractylone, 3β-hydroxyatracetylone[4], butenoliede B[5], tryptophane, 35-dimethoxy-4-glucosyloxyphenylallylalcohol, 2-14α-dimethyl-3-glucosyloy-2-oxo-2,3,4,4α5,6,7,8-octahydronaphthalen-7-yl-isopropanolglucoside, 2-[8-methyl-2,8,9-trihydroxy-2-hydroxymethyl-bicyclo[5.3.0]decan-7-yl]isopropanogllucoside,2-[8-methyl-2,8-dihydroxy-9-oxo-2-hydroxymethylbicyclo[5,3,0]decan-7-yl]isopropanolglucoside,2-14α-dimethyl-2,3-dihydroxydec-ahydroxynaphthalen-7-yl)isopropanolglucoside[6];

It also contains inorganicelements[7].

 
[Pharmacological activities]

1. Effect on Digestive System: Atractylodes chinensis extract can inhibit constriction of guinea pigs or rat ileal induced by K+ ,Ga+ and Carbachol[1-3]. TDEYA extract show protect fountion on experimental stomach ulcer rat model[4].

2. Hepatoprotection: Its extract show prophylaxis effect on carbon tetrachloride induced rat liver cell damge[4]. Atractylon can resistance liver DNA damage and toxic by tert-butyl peroxides[5].

3. Hypoglycemic: Atractyloside show hypoglycemic activity throuogh inhibit pasteur effect. Atractan A, B and C can cut down blood sugar level on diabetes rats induced by alloxan[6]. Water extract can enhance utilize powder ability on diabetes rats induced by streptozotocin[7].

4. Antimicrobial: Atractylodes chinensis show bacteriostasis on staphylococcus aureus, tubercle bacillus, escherichia coli, dried leaves bacterium, aeruginosus bacillus, Saccharomyces albicans, Trichophyton rubrum, Trichophyton gypseum and so on. Atractyylodes chinensis extract show bacteriostasis on resistance bacillus dysenteriae[8].

5. Diuresis: β-eudesmol machilol show diuresis activity through inhibit Na+ -K+ -ATP enzyme[1].

6. Anti-Anoxia: Acetone extract show anti-hypoxia effect on KCN induced mice model. And the β-eudesmol may the activity compound[1].

7. Anti-inflammatory Action: Acetic ether extract show non-specificity anti-inflammatory action. In addition, Selina-4(14), 7(11)-dien-8-one, atraactylenolide,, show anti-inflammatory action also[1].

8.Effect on Nervous System: Volatile oil show sedation at low dose and then respiratory paralysis at large dose on rana. β-eudesmol can block acetylcholine receptor[1].

9. Antiarrythmic: N-butanol extractant can agonistic rat arrhythmia induced by myocardial ischemia, ischemia-reperfusion, aconitine, barium chloride and ouabain[1].

 
[Clinical trial]

1. Prevent colds: Cangzhu fufang, Cangzhu (Atractylodes  Rhizoma ),to observe 679 cases, results in a cold person accounted for only 7%or so .

 

2.Treatment of conjunctival xerosis: Cangzhu (Atractylodes  Rhizoma ) powder 3 g, children reduction. Treat nyctalopia conjunctival xerosis42 cases of patients, for 2 ~ 3 d symptoms was disappeared. The early treatmentof conjunctival drying syndrome patients 35 patients for 3 ~ 4 d; Cornealdrying period of eight people, take medicine  for 4 ~ 5 d, self-conscious symptom andconjunctival damage all disappear.

3. Treatment of rickets:(1) Cangzhu (Atractylodes  Rhizoma ) 500 g and Jidanpifen 56g were made to Cangzhutangjiang 560ml, for treatmentof 1006 cases of infantile rickets. Results: 541 cases were markedly effective(53.8%);340 cases were effective , accounting for 33.7%; 125 cases were invalid,accounting for 12.4%; The total effective rate was 87.5%。 

 
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[Medical and other Uses]  
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[Cautions]  
[Traditional usage]  
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[References]

Pharmacologic Actions:

[1] Zhao Aimei. Guangming Journal of Chinese Medicine, 2009,24.(1):181.

[2] Aoki Junji. International Journal of Traditional Chinese Medicine, 1991,13(2): 59.

[3] Li Wei, Zheng Tianzhen. Pharmacology and Clinics of Chinese Materia Medica, 2000,16(5):20-27.

[4] Zhang Jun.  International Journal of Traditional Chinese Medicine, 1996,18(5):46.

[5] Zhang Qiuhua. LiShiZhen Medicine and Materia Medica Research, 1997, 8( 6) : 505 ) 506.

[6] Li Manling. Chinese Journal of Information on Traditional Chinese Medicine, 2002. 9( 11) : 80 ) 82.

[7] Zhou Dewen.. World Phytomedicines, 1996,11(3):120.

[8] Gao Bin, Du Wen. Chinese Journal of Traditional Medical Science and Technology, 1998,5(3):162.

Clinical trials:

[1] Lanzhou medical schoolattached two hospital respiratory group. Chinese Journal of Internal Medicine.1976.(5):285

 [2] JIN Nang. Clinicalprescription highlights (contd a). The first edition. Fuzhou:fujianscience and technology press.1984:242

 [3] Jinan children's hospitalrickets control group. Etc. Barefoot doctor magazine.1979.(10):14