[English Name] | katsumade Galangal Seed | |
[Chinese Name] | 草豆蔻 | |
[Pinying Name] | Caodoukou | |
[Latin Name] | Semen Alpiniae | |
[Genera] | Zingiberaceae | |
[Efficacy] | huashiyao | |
[Pictures] | Plant picture | Drug picture |
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[Alias] | ||
[Source] | 1.Alpinia Katsumadai Hayata 2.A.blepharocalyx.K.Schum. | |
[Plant morphology] | ||
[Distribution] | ||
[Gathering and processing] | ||
[Characteristics] | ||
[Ecology] | It grows mostly in dank area of ravine,mostly cultivated under the tree shade in China. | |
[Chemical composition] | This plant contains flavanoid: kaempferol, quercetin, rhamnocitrin, kumatakenin[1], alpinetin, cardamonin, pinocembrin[1-3], quercetin-3-O-(2,6-di-O-rhamnopyranosyl galactopyranoside), isorhamnetin-3-O-(2,6-di-O-rhamnopyranosylgalactopyranoside), pinocembrin-3,7-di-β-D-glucoside, quercetin 3-O-robinobioside, catechin, adenosine, uracil, nicotinic acid, hypoxanthine, adenine[5]; diphenylheptane: (5R)-trans-1,7-diphenyl-5-hydroxy-6-hepten-3-one, (3S,5S)-trans-1,7-diphenyl-3,5-dihydroxy-1-heptene, trans-1,7-diphenyl-5-hydroxy-1-heptene, (3S,5R)-3,5-dihydroxy-1,7-diphenylheptane[1], trans,trans-1,7-diphenyl-5-hydroxy-4,6-heptadien-3-one, trans,trans-1,7-diphenyl-4,6-heptadien-3-one)[1-3]; aetherolea: trans-cinnamaldehyde, α-humulene, linalool, camphor, 4-terpineol, carvotanacetone, methyl cinnamate, bornyl acetate, geranyl acetate, nerolidol, limonene, borneol[1], 1,8-cineole, α-pinene, β-pinene, camphene, farnesol[1,4], 3-carene, 3,7-dimethyl-1,6-octadiene-3-ol, α,α,4-trimethyl-3-cyclohexene-1-methanol, 3-phenyl-2-butanone, α-caryophyllene, bisabolene, β-cadinene, farnesol, hexadecanoic acid, cis-para-menth-2-en-1-ol, lavandulol, cubenol[4]; trace element: Cu, Fe, Mn, etc [1]; The fruits contains 7,4′-dihydroxy-5-methoxy flavanone[3], β-sitosterol[2]. |
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[Pharmacological activities] |
1. Antioxidant: katsumade Galangal Seed extractive scavenging DPPH radical activity strongly, the IC 50 for 1.6μg/mL; also enhance viability of Chinese hamster lung fibroblasts (V79-4), inhibit hydrogen peroxide induced withered death; dose-dependent enhanced V79-4 cell activity of superoxide dismutase(SOD), over catalase (CAT) and glutathione peroxidase (GPX) [1]. 2. Effects on gastric acid secretion: 10% of katsumade Galangal Seed lixivium had no significant effect on total acid output of the three links Pavlov stomach dog, but will enable the vitality of pepsin significantly increased [2]. |
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[Clinical trial] | ||
[Properties] | ||
[Medical and other Uses] | ||
[Dosage] | ||
[Cautions] | ||
[Traditional usage] |
1. Vomiting induced by cold phlegm, oppression in chest 2. Distention in chest and abdomen, shortness of breath 3. Poor appetite due to spleen and stomach deficiency, vomiting, pain in chest and abdomen 4. Abdominal pain caused by yang deficiency of large intestine, poor appetite 5. Miasma 6. Infantile cholera |
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[Toxicological studies] | ||
[Pharmaceutical preparations] |
1. Huoluo Pill:long-nosedpit viper(stir-frying with wine), black-tail snake(stir-frying with wine),earthworm, scorpion, clematis root(stir-frying with wine), prepared aconiteroot(stir-frying), chinese cassia bark(remove the peel), nutgrass flatsedgerhizome, asarum herb, ephedra, notopterygium root, dahurian angelica root,ledebouriella root, colophony, agastache, katsumada galangal seed, roundcardamon seed, lindera root, aucklandia root, eagle wood, colophony, clove,green tangerine orange peel(stir-frying with vinegar), nutgrass flatsedgerhizome(stir-frying with vinegar), red peony root, myrrh(stir-frying withvinegar), frankincense(stir-frying with vinegar), draconis resin, musk,benzoin, borneol, gastrodia tuber, tabasheer, turmeric(stir-fryingwith bran), coptis root, scutellaria root,pueraria root, rhubarb(steaming), scrophularia root, pulvis cornus bubaliconcentratus, cinnabar, artificial cow-bezoare, ginseng, white atractylodesrhizome(stir-frying with bran),poria, liquorice, prepared rehmannia root, chinese angelica root, chuanxiongrhizome, fleece flower root(stir-frying with soybean wine), fortune’s drynariarhizome, tortoise carapace and plastron(heated with sandcalcining and quenching with vinegar), dog’sbone(stir-frying with oil). 2. Weide’an Tablet:white atractylodesrhizome, atractylodes rhizome, poria, immature bitter orange, aucklandia root,magnolia bark, dried human placenta, liquorice, medicated leaven, germinatedbarley, ginger processed pinellia, tangerine peel(prepared), nutgrass flatsedgerhizome(prepared), chuanxiong rhizome, katsumada galangal seed, areca seed,radish seed, snakegourd fruit, oriental water plantain rhizom, scutellariaroot, phellodendron bark, all-grass of Indian kalimeris, dried ginger, seed ofJapanese calangal, cuttlebone. 3. Yuzhiping’an Pill: atractylodesrhizome(stir-frying), magnolia bark(prepared), tangerine peel, immature bitterorange(stir-frying), eagle wood, clove, aucklandia root, sandalwood, red roundcardamon seed, katsumada galangal seed, nutmeg, hawthorn fruit(stir-frying),medicated leaven, germinated barley(stir-frying), liquorice. 4. Yangweining Capsule: nutgrassflatsedge rhizome(processing with vinegar), citron fruit, aucklandia root,ginseng, round cardamon seed, katsumada galangal seed, chinese angelica root,pirnce’s-feather fruit(stir-frying), trogopterus dung, rhubarb, radishseed(stir-frying), stir-fried liquorice. 5. Renshenzaizao Pill(CondensedPill) : ginseng(removingLU), milkvetch root, white atractylodes rhizome(stir-fryingwith bran), poria, prepared fleece flowerroot, chinese angelica root, prepared rehmannia root, tortoise carapace andplastron(prepared), leopard bone(prepared), loranthus mulberry mistletoe,fortune’s drynaria rhizome(stir-frying), gastrodia tuber, bile arisaema,batryticated silkworm(stir-frying), earthworm, scorpion, tabasheer,notoginseng, chuanxiong rhizome, red peony root, turmeric, frankincense(processingwith vinegar), myrrh(processing with vinegar), draconis resin, long-nosed pitviper(processing with shaoxing wine), dahurian angelica root, notopterygiumroot, clematis root, ephedra, ledebouriella root, pueraria root, yam rhizome,asarum herb, clove, lindera root, green tangerine orange peel, eagle wood,nutgrass flatsedge rhizome(processing with vinegar), sandalwood, katsumadagalangal seed, round cardamon seed, pummelo peel, agastache, medicated leaven(stir-fryingwith bran), prepared aconite root, chinesecassia bark, musk, borneol, cinnabar(grinding in water), amber, cow bezoare,buffalo hornenriched liquid, coptis root, rhubarb, scrophularia root,liquorice. 6. Kangshuang Zaizao Pill: leech(scalding),red sage root, notoginseng, earthworm, pangolin scales(scalding), achyranthesroot, rhubarb, peach kernel, safflower, ground beetle, pueraria root, musk,borneol, storax, cow bezoare, bile arisaema, scorpion, black-tail snake, gastrodiatuber, asarum herb, Chuanlong Yam, clematis root, red ginseng, milkvetch root,chinese angelica root, fleece flower root, cinnabar, katsumada galangal seed,liquorice. 7. Yizhong Shengxue Tablet: dangshen,chinese yam, coix seed(stir-frying), chinese date, copperas, tangerine peel,processed pinellia tuber, katsumada galangal seed, liquorice. 8. Jianpi Xiaoshi Pill: whiteatractylodes rhizome(stir-frying), cinnabar(stir-frying), aucklandia root,areca seed(stir-frying), katsumada galangal seed, membrane of chickengizzard(stir-frying with vinegar), eleocharis tuberosa powder. 9. Zaizao Pill: ginseng,milkvetch root, white atractylodes rhizome, prepared fleece flower root,prepared rehmannia root, chinese angelica root, scrophularia root, tortoisecarapace and plastron, fortune’s drynaria rhizome, loranthus mulberrymistletoe, borneol, musk, artificial cow-bezoare, coptis root, cinnabar,buffalo hornenriched liquid, clematis root, leopard bone, dahurian angelicaroot, notopterygium root, ledebouriella root, ephedra, asarum herb, yamrhizome, long-nosed pit viper, pueraria root, rhizoma anemones raddeanae,tabasheer, musk, round cardamon seed, katsumada galangal seed, poria, clove,eagle wood, sandalwood, lindera root, nutgrass flatsedge rhizome, greentangerine orange peel, pummelo peel, prepared aconite root, chinese cassiabark, gastrodia tuber, scorpion, chuanxiong rhizome, rhubarb, red peony root,pangolin scales, common aucklandia root (prepared), myrrh(prepared), turmeric,pine nodular branch, jian medicated leaven, red colouring rice used as achinese medicine, liquorice. 10. Jianwei Tablet:bupleurumroot, atractylodes rhizome(processing with rice water), katsumada galangalseed, tangerine peel, corydalis tuber(processing with vinegar), sichuanchinaberry, white peony root, hawthorn fruit(stir-frying), membrane of chickengizzard(stir-frying with vinegar), medicated leaven(stir-frying), germinatedbarley(stir-frying), areca seed(stir-frying), fresh ginger, liquoriceextractum. |
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[References] | Chemical Composition:[1] State Administration Of Traditional Chinese Materia Medica Editorial Board."" Chinese Materia Medica. Shanghai: Shanghai Science And Technology Press,1999,24:596( Total7748).[2] Wang Xiuqin, Yang Xiaojiang, Li Education Agency . Grass Cardamom Studies On Chemical Constituents Of Chinese Herbal Medicine,2008,31(6):853[3] Ding Xingbao, Zhong Ying, Wang Xiaojing, Et Al. Studies On The Chemical Constituents Of Grass Cardamom ( I ). Chinese Herbal Medicine,1997,28(6):333[4] Yu Ping, Cui Zhaojie, Qiu Qin, Et Al. Grass Nutmeg Volatile Oil Chemical Composition GC/MS. Chinese Journal Of Modern Applied Pharmacy,2002,19(2):135[5] Li Yuanyuan, Guixin, Wang Zhengtao Grass Cardamom Butanol Fractions Of Chemical Components. Chinese Journal Of Natural Medicine,2009,7(6):417Pharmacological Effect:[1] Wang Ming . Grass Cardamom Antioxidant Activity Of Extracts From Foreign Medicine ( Chinese Medicine Part ),2005,17(12):1041[2] Li Zailiu, Jin Zezhong,Li Jijun. Clove, Galangal, Grass Nutmeg On Gastric Secretion In Rats. Journal Of TCM,1980,2(2):68Clinical Trials:Toxicology:[1] Zhao Xiaofeng, Wu Youliang, Peng Yao, And So On. Acute Toxicity Test Of [J]. Chinese Pharmacist .2010,13(L):65-66[2] Wei Guining, Zhou Jun, He Fei. Kang Fu Gan Granule On Mice With Spleen Deficiency Syndrome Of Emergency And Acute Toxicity Experimental Study [J]. Chinese Medicine,2010,13(8):1098- 1100 |