Location:Home > Rose > [Chinese]
[English Name] Rose
[Chinese Name] 玫瑰花  
[Pinying Name] Meiguihua  
[Latin Name] Rosa rugosa  
[Genera] Rosaceae
[Efficacy] Qi-regulating drug
[Pictures] Plant picture Drug picture
Plant picture
 
Drug picture
 
[Alias]  
[Source]  
[Plant morphology]  
[Distribution]  
[Gathering and processing]  
[Characteristics]  
[Ecology]     Rose is temperate tree species, resisitants to cold and drought,no strict damand of soil,grows in alkalescence soil,the best growth and flowering is in neutral or  subacid soil land with rich humus and good drainage.It most prefers light,grows unwell under the shade, less flowering,doesn’t resistant to water, the lower leaves are yellow and falling when waterlogged,strong ability of sprouting,grows rapidly.  
[Chemical composition]  
[Pharmacological activities]

1. The role of the cardiovascular system: the roses total extract topical application to increase micro-artery blood flow velocity, for venule is not obvious. Added adrenaline can lead to mouse mesenteric microcirculation, the total extract of the local dropping roses, can speed up the microcirculation of recovery. Roses the total extract of the above roles is similar to Danshen injection but weaker [1]. Acidic and neutral rose water decoction can be a remarkable expansion of noradrenaline precontracted aortic smooth muscle, and this effect is similar to the 10-5 mol / L acetylcholine; removal of endothelial cells, 10-4 mol / LN-nitro left spin arginine or 10-5 mol / L methylene blue can completely eliminate roses vasodilator effect, but 10-5 mol / L indomethacin and propranolol have no significant effect. That shows rose water decoction allows expansion of vascular smooth muscle, the role is endothelium-dependent and related with nitric oxide (NO) [2]. Xinjiang rose decoction 5.2g/kg orally can significantly reduce the ECG ST-segment elevation in the experimental animals chemic, against rat acute myocardial ischemic change induced by isoproterenol. Protect the superoxide dismutase (SOD) activity of ischemic myocardium, showing its anti-lipid peroxidation, meanwhile inhibit the release of myocardial creatine kinase, and reduce oxygen free radical damage to the myocardial cell membrane caused by damage [3]. With roses main compound Roses capsule can significantly increase myocardial ischemia and reperfusion injury of nitric oxide synthesis in the myocardial tissue content of enzymes and glutathione peroxidase (GSH-PX), and content [4] or high serum GSH-PX and reduce hydrogen peroxide in the serum [5], elevated plasma 6 - keto prostaglandin F1 alpha (6-Keto-PGF 1α), calcitonin gene-related peptide and lower plasma levels of thromboxane prime B2 (TXB 2 ), endothelin (ET) [6] increased the serum SOD activity and nitric oxide (NO) levels and lower serum Ca2+ content [7], and thus has a protective effect on reperfusion myocardial injury.

2. Antibacterial and anti-virus: decoction of rose water inhibit Staphylococcus aureus, Salmonella typhi and Mycobacterium tuberculosis; roses extracts have anti-virus on the human immunodeficiency virus, leukemia virus and T-cell leukemia virus role. Which contains the long-stemmed of aristolochic factors and suona factors that can inhibit the infection of cells of murine leukemia virus reverse transcriptase. Mice fed the median lethal volume of these two kinds of ingredients is greater than 100mg/kg [8].

3. Antioxidant: Rose water extract powder rapid aging model mice (SAM-P/8) administered 42 days after the 80mg/kg dose of 3, 6, and 8 months of age, the mice over the 8-month-old anti- the effect of oxidation, and mice to inhibit the ability of red blood cell hemolysis, while also reduce hepatic malondialdehyde (MDA) content, and enhance the activity of SOD, significantly increase the expression of SOD gene [9].

4. Treatment of dysmenorrhea: Shujing Mei Gui-based capsules with roses have a protective effect in mice with primary dysmenorrhea [10], the mechanism of action related to reducing uterine tissue homogenates of MDA, Ca2+ ET content and increasing uterine NO content in tissue homogenates[11-12], increasing SOD activity and lower content of oxygen free radicals [13], elevating serum GSH-PX with the content of NO [14] and increasing in plasma 6-Keto-PGF  content and reducing the TXB 2 content [15].

5. Others: Rose oil can promote the secretion of bile in rats, and can significantly improve the recovery of hepatitis and cholecystitis, cholelithiasis, exacerbation of the symptoms [16]. Catechin substances vitamin P-like role, can be used for the comprehensive treatment of radiation sickness, and with anti-tumor effect [17].

 
[Clinical trial]  
[Properties]  
[Medical and other Uses]  
[Dosage]  
[Cautions]  
[Traditional usage] 1.Early sore and boil 2.Mastitis 3.Traumatic injury, rheumatic arthritis, pain on waist and legs 4.Headache caused by liver fire 5.Lung disease with cough and hemoptysis 6.Distending pain in chest and hypochondrium due to qi stagnation 7.Pain in stomach and liver due to qi stagnation 8.Foreign body sensation in throat induced by esophagospasm 9.Enteritis with diarrhea 10.Irregular menstruation 11.Morbid leucorrhea  
[Toxicological studies]  
[Pharmaceutical preparations]  
[References]

chemical composition:

[1] state administration of traditional chinese medicine of the people’republic of china.chinese herbaleditorial board. chinese. shanghai: shanghai science and technology press,1999,10:240(2807).

pharmacological action:

[1] wang jun, yue xiangdong, jiang jiqiang et al. influence of extract of rosa rugusa thunb on the mesenteric microcirculation in mice. shandong journal of biomedical engineering,1997,16(4):20.

[2] li hongfang, pang jinjiang, ding yonghui, et al. tensive effect of water decoction of flos rosae rugosae on the rabbit aorta in vitro. pharmacology and clinics of chinese materia medica,2002,18(2):20.

[3] li yujing,yang yongxin,kang jinguo.xinjiang roses, c. deserticola rat myocardial ischemia of protection[j]. xinjiang journal of traditional chinese medicine,1998,16(1):49.

[4]zhang yanping,yao ning,deng yi.the experiments of compound rose capsule of rabbit myocardial ischemia and reperfusion injury.chinese journal of experimental traditional medical formulae,2006,12(4):45.

[5] yao ning,wang xin,liu jianhong,etal. experimental study of fufang meigui capsule’s effects on gsh-px and h2o2 in the blood serum of rabbits damaged by myocardial ischemia and reperfusion. journal of gansu college of traditional chinese medicine,2005,22(4):19.

[6] wang xin. effect of red rose capsule compound on plasma thromboxane b2, 6-keto-prostaglandin f1α and calcitonin gene related peptide in the rabbits myocardial ischemia-reperfusion injury. chinese journal of information on tcm,2004,11(6):491.

[7]liu jianhong,wang xin,chen yanwen,etal.the experimental study of compound rose capsule on myocardial ischemia-reperfusion injury of sod no, of ca2 + effects[j]. chinese journal of clinical medical research, 2003,(92)4.

[8]li ming,li yanfang,sun yongchao. progress in traditional chinese medicine roses. health vocational education,2007,25(8):146,

[9] niu shumin, zhu songhua, li wei,etal. studies on atioxidant effects and mechanism of chinese herb rosa rugosa thunb. acta scientiarun naturaltium universitatis nankaiensis,2004,37(2):29.

[10] pei peitian,wang xin,chen yan wen,etal.shujing mei gui capsules in mice with primary dysmenorrhea sedation and analgesia[j].

clinical trials:

[1]yu baodian,sun lian,cao yue zhen,etal.the comparation of rose runchang treatment of functional constipation[j]. shanghai journal of traditional chinese medicine,1998,(l2):19.

[2] zhang xiu-lan,etal. preliminary exploration on rose shu-xin oral liquid in treating angina pectoris of chd. chinese journal of integrated traditional and western medicine,1992,12(7):414.

[3] liu xinguang,liu zhilin.the clinical observation of 100 cases of rose dysmenorrheal spiritual treatment of dysmenorrheal[j].chinese journal of traditional medical science and technolog,2003,l0(1):21.

toxicology: